[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100589779":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":54,"centralContacts":61,"locations":70,"responsibleParty":87,"collaborators":49,"id":89,"slug":49,"hasResults":90,"nctId":91,"briefTitle":92,"officialTitle":93,"acronym":94,"eligibilityCriteria":95,"healthyVolunteers":90,"sex":96,"minAge":97,"maxAge":49,"enrollmentInfo":98,"targetDuration":49,"studyType":101,"phases":102,"briefSummary":104,"conditions":105,"keywords":108,"overallStatus":73,"whyStopped":49,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":122},{"fullName":5,"class":6},"University Hospital, Basel, Switzerland","OTHER",[8,15,20,25],{"label":9,"type":10,"description":11,"interventionNames":12},"16F - early removal","EXPERIMENTAL","small-bore (16F) chest tubes, removal 2h until 6h after end of skin closure",[13,14],"Device: 16 F chest tube","Procedure: Early removal",{"label":16,"type":10,"description":17,"interventionNames":18},"16F - standard removal","small-bore (16F) chest tubes, removal 1 day postoperative",[13,19],"Procedure: Standard removal",{"label":21,"type":10,"description":22,"interventionNames":23},"24F - early removal","large-bore (24F) chest tubes, removal 2h until 6h after end of skin closure",[24,14],"Device: 24 F chest tube",{"label":26,"type":27,"description":28,"interventionNames":29},"24F - standard removal","ACTIVE_COMPARATOR","large-bore (24F) chest tubes, removal 1 day postoperative",[24,19],[31,38,44,50],{"type":32,"name":33,"description":34,"armGroupLabels":35,"otherNames":36},"DEVICE","16 F chest tube","Insertion of 16F chest tube",[9,16],[37],"Small-bore chest tube",{"type":32,"name":39,"description":40,"armGroupLabels":41,"otherNames":42},"24 F chest tube","Insertion of 24F chest tube",[21,26],[43],"Large-bore chest tube",{"type":45,"name":46,"description":47,"armGroupLabels":48,"otherNames":49},"PROCEDURE","Early removal","Removal 2-6h after end of skin closure",[9,21],null,{"type":45,"name":51,"description":52,"armGroupLabels":53,"otherNames":49},"Standard removal","Removal 1day postoperative",[16,26],[55,58],{"name":56,"affiliation":5,"role":57},"Didier Lardinois, MD","STUDY_CHAIR",{"name":59,"affiliation":5,"role":60},"Makhmudbek Mallaev, MD","PRINCIPAL_INVESTIGATOR",[62,67],{"name":63,"role":64,"phone":65,"phoneExt":49,"email":66},"Helga Bachmann, MSc Clinical Research","CONTACT","+41 (0)61 328 71 70","helga.bachmann@usb.ch",{"name":59,"role":64,"phone":68,"phoneExt":49,"email":69},"+41 (0)61 556 51 89","makhmudbek.mallaev@usb.ch",[71],{"facility":72,"status":73,"city":74,"state":49,"zip":75,"country":76,"cosmosGeoPoint":77,"geoPoint":82,"contacts":83},"University Hospital Basel","RECRUITING","Basel","4031","Switzerland",{"type":78,"coordinates":79},"Point",[80,81],7.57327,47.55839,{"lat":81,"lon":80},[84,85],{"name":63,"role":64,"phone":65,"phoneExt":49,"email":66},{"name":86,"role":64,"phone":68,"phoneExt":49,"email":69},"Mallaev Makhmudbek, MD",{"type":88,"investigatorFullName":49,"investigatorTitle":49,"investigatorAffiliation":49,"oldNameTitle":49,"oldOrganization":49},"SPONSOR","100589779",false,"NCT06958848","16F vs 24F Chest Drain After Minimally Invasive Lobectomy and\u002For Segmentectomy","Comparison of 16F Versus 24F Chest Drain After Minimally Invasive Pulmonary Lobectomy and\u002For Segmentectomy: a Monocentre Prospective Randomized Controlled Trial","ChestDrain","Inclusion Criteria:\n\n* Informed Consent signed by the patient (all sex and gender)\n* Patients' age from ≥ 18 to no age limit at time of study inclusion\n* American Society of Anaesthesiologists (ASA) physical status classification I to IV\n* Patients with resectable non-small cell lung cancer (NSCLC) deemed operable by minimally invasive surgical technique.\n* Minimally invasive anatomical lung resections under general anaesthesia: lobectomy, lobectomy with wedge resection, lobectomy combined with segmentectomy, segmentectomy with wedge resection, bilobectomy\n\nExclusion Criteria:\n\n* Previous thoracic surgery on the same side within 3 months\n* Lung cancer complicated with pleural empyema\n* Patients with chronic pain who receive opioids\u002Fgabapentin\u002Fpregabalin\n* Patients who consume opiates\u002Fbenzodiazepines\n* Congestive heart failure NYHA Class III or IV\n* Liver cirrhosis Child-Pugh Class B and C\n* Renal insufficiency requiring dialysis and\u002For estimated glomerular filtration rate (eGFR) \\\u003C30 mL\u002Fmin\u002F1.73 m2\n* Patients with coagulopathy or bleeding disorders: von Willebrand disease, Hemophilia; Thrombocytopenia (\\\u003C50 G\u002Fl), requiring platelet transfusion\n* Patients with neuralgia\n* Chest pain (site of surgery) without taking painkillers, measured by VAS while coughing \\> 10 mm\n* Not consolidated rib fractures (in the last 3 months) on the side of surgical procedure\n* Open anatomical lung resection, including pneumonectomy\n* Insertion of 2 or more chest tubes\n* Need for patient controlled intravenous anaesthesia or patient controlled epidural anaesthesia\n* Patients intubated\u002Fsedated (not suitable due to difficulties to fill out the pain survey)","ALL","18 Years",{"count":99,"type":100},124,"ESTIMATED","INTERVENTIONAL",[103],"NA","The aim of the study is to evaluate postoperative pain in patients receiving a small-bore (16F) chest drain compared to those receiving the standard large-bore (24F) chest drain after minimally invasive pulmonary lobectomy and\u002For segmentectomy.",[106,107],"Pneumothorax","Pleural Effusion",[109,110,111,112],"Lung Surgery","Chest Drainage","Minimally Invasive Thoracoscopic Lobectomy","Minimally Invasive Thoracoscopic Segmentectomy","2026-04-30",{"date":115,"type":116},"2026-05-06","ACTUAL",{"date":118,"type":116},"2025-05-01",{"date":120,"type":100},"2027-08-30",{"name":5,"class":6},1]