This purpose of this study is to determine the ability of an 18F-fluoro-L-dihydroxyphenylalanine (18F-DOPA) PET (Positron Emission Tomography) scan to detect a focal lesion of hyperinsulinism and determine the location in patients with congenital hyperinsulinism, Beckwith Wiedemann Syndrome and suspected insulinoma. Safety data will be collected.
Subjects of any age with hyperinsulinemic hypoglycemia, diagnosed by a fasting test and/or response to glucagon stimulation.
Subjects who are eligible for pancreatic surgery regardless of prior pancreatic surgery
Pregnant or lactating females
Any other major illness or condition that in the investigator's judgment will substantially increase the risk associated with the subject's participation in this study
Subjects who are not a candidate for pancreatic surgery
Children's Hospital of Philadelphia
Lead sponsor