[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100202772":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":16,"centralContacts":20,"locations":29,"responsibleParty":44,"collaborators":7,"id":47,"slug":7,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":7,"eligibilityCriteria":52,"healthyVolunteers":48,"sex":53,"minAge":7,"maxAge":7,"enrollmentInfo":7,"targetDuration":7,"studyType":54,"phases":7,"briefSummary":55,"conditions":56,"keywords":60,"overallStatus":31,"whyStopped":7,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":7,"completionDateStruct":7,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Children's Hospital of Philadelphia","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":13},"DRUG","18F-DOPA","18F-DOPA is a PET (Positron Emission Tomography) scan radiotracer.",[14,15],"18F-fluoro-L-dihydroxyphenylalanine","18F-L-Fluoro-DOPA",[17],{"name":18,"affiliation":5,"role":19},"Lisa States, MD","PRINCIPAL_INVESTIGATOR",[21,26],{"name":22,"role":23,"phone":24,"phoneExt":7,"email":25},"Susan Becker, RN, BSN, CCRC","CONTACT","267-426-0269","Beckers@chop.edu",{"name":18,"role":23,"phone":27,"phoneExt":7,"email":28},"267-425-7146","States@chop.edu",[30],{"facility":5,"status":31,"city":32,"state":33,"zip":34,"country":35,"cosmosGeoPoint":36,"geoPoint":41,"contacts":42},"AVAILABLE","Philadelphia","Pennsylvania","19104","United States",{"type":37,"coordinates":38},"Point",[39,40],-75.16362,39.95238,{"lat":40,"lon":39},[43],{"name":18,"role":19,"phone":7,"phoneExt":7,"email":7},{"type":19,"investigatorFullName":45,"investigatorTitle":46,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Lisa States","Principal Investigator","100202772",false,"NCT01916148","18F-L-Fluoro-DOPA PET\u002FCT Scan Localization of Focal Pancreatic Lesions in Subjects With Hyperinsulinemic Hypoglycemia","Expanded Access Use of 18F-L-Fluoro-DOPA PET\u002FCT Scan Localization of Focal Pancreatic Lesions in Subjects With Hyperinsulinemic Hypoglycemia","Inclusion Criteria:\n\n* Subjects of any age with hyperinsulinemic hypoglycemia, diagnosed by a fasting test and\u002For response to glucagon stimulation.\n* Subjects who are eligible for pancreatic surgery regardless of prior pancreatic surgery\n\nExclusion Criteria:\n\n* Pregnant or lactating females\n* Any other major illness or condition that in the investigator's judgment will substantially increase the risk associated with the subject's participation in this study\n* Subjects who are not a candidate for pancreatic surgery","ALL","EXPANDED_ACCESS","This purpose of this study is to determine the ability of an 18F-fluoro-L-dihydroxyphenylalanine (18F-DOPA) PET (Positron Emission Tomography) scan to detect a focal lesion of hyperinsulinism and determine the location in patients with congenital hyperinsulinism, Beckwith Wiedemann Syndrome and suspected insulinoma. Safety data will be collected.",[57,58,59],"Congenital Hyperinsulinism (CHI)","Beckwith-Wiedemann Syndrome","Insulinoma",[61,62,63,64,65,15,14,66,67,68,69,70,71,72],"Hypoglycemia","Hyperinsulinism (HI)","F-DOPA","PET","18-F DOPA","focal pancreatic lesions","congenital hyperinsulinism","Beckwith Wiedemann Syndrome","insulinoma","Hyperinsulinemic Hypoglycemia","F-DOPA PET","CHI (Congenital hyperinsulinism)","2026-04-22",{"date":75,"type":76},"2026-04-27","ACTUAL",{"name":5,"class":6},1]