[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100549320":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":27,"locations":35,"responsibleParty":57,"collaborators":59,"id":62,"slug":19,"hasResults":63,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":19,"eligibilityCriteria":67,"healthyVolunteers":63,"sex":68,"minAge":69,"maxAge":19,"enrollmentInfo":70,"targetDuration":19,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":82,"overallStatus":37,"whyStopped":19,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Royal North Shore Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Gynaecological HDR brachytherapy patients","EXPERIMENTAL","Using 3D-printed custom applicators to treat gynaecological HDR brachytherapy patients",[13],"Device: 3D-printed custom applicator",[15],{"type":16,"name":17,"description":17,"armGroupLabels":18,"otherNames":19},"DEVICE","3D-printed custom applicator",[9],null,[21,24],{"name":22,"affiliation":5,"role":23},"Marita Morgia, MD","PRINCIPAL_INVESTIGATOR",{"name":25,"affiliation":5,"role":26},"Jeremy Booth, PhD QMP","STUDY_DIRECTOR",[28,32],{"name":22,"role":29,"phone":30,"phoneExt":19,"email":31},"CONTACT","9463 1300","Marita.Morgia@health.nsw.gov.au",{"name":25,"role":29,"phone":33,"phoneExt":19,"email":34},"94631300","jeremy.booth@health.nsw.gov.au",[36],{"facility":5,"status":37,"city":38,"state":39,"zip":40,"country":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"RECRUITING","St Leonards","New South Wales","2067","Australia",{"type":43,"coordinates":44},"Point",[45,46],151.19836,-33.82344,{"lat":46,"lon":45},[49,53],{"name":50,"role":29,"phone":51,"phoneExt":19,"email":52},"Carol Kwong","02 9463 1339","Carolyn.Kwong@health.nsw.gov.au",{"name":54,"role":29,"phone":55,"phoneExt":19,"email":56},"Heidi Tsang","02 9463 1340","Heidi.Tsang@health.nsw.gov.au",{"type":58,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR",[60],{"name":61,"class":6},"Northern Sydney and Central Coast Area Health Service","100549320",false,"NCT06432478","3D Printed Custom Applicators for HDR BT (DISCO)","Study of 3D-printed Custom Applicators for Intracavitary HDR Gynaecological Brachytherapy (DISCO)","Inclusion Criteria:\n\n* Able to give informed consent\n* Patients indicated for intracavitary brachytherapy\n* FIGO stage I-IVA\n* ECOG 0-2\n* Primary endometrial cancer, primary vaginal cancer, primary vulva cancer, recurrent gynaecological cancer\n\nExclusion Criteria:\n\n* Pregnancy\n* Patients contraindicated for brachytherapy\n* Inflammatory bowel disease\u002Fhistory of adhesions\u002Fbowel obstruction\n* Renal transplant\u002Fhorseshoe kidney\n* Patients with significant LVSI or pelvic sidewall invasion\n* Patients requiring interstitial brachytherapy implants","FEMALE","18 Years",{"count":71,"type":72},10,"ESTIMATED","INTERVENTIONAL",[75],"NA","Intracavitary brachytherapy for gynaecological cancer currently use cylinder-type applicators or custom wax moulds to place a radioactive source in close proximity to the treatment area and provide highly conformal dose distributions. This study is a Phase IIa non-randomised interventional pilot trial that will investigate the feasibility of successfully treating patients with 3D-printed custom applicators.",[78,79,80,81],"Gynecologic Cancer","Endometrial Cancer","Vaginal Cancer","Vulva Cancer",[83,84,85],"3D-printed applicator","Gynaecological Cancer","Brachytherapy","2026-02-04",{"date":88,"type":89},"2026-02-06","ACTUAL",{"date":91,"type":89},"2023-11-24",{"date":93,"type":72},"2028-09",{"name":5,"class":6},1]