[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100506391":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":21,"centralContacts":26,"locations":31,"responsibleParty":50,"collaborators":20,"id":52,"slug":20,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":20,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":58,"minAge":59,"maxAge":20,"enrollmentInfo":60,"targetDuration":20,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":71,"overallStatus":33,"whyStopped":20,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"The First Affiliated Hospital of Xiamen University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"68Ga-FAPI-LM3","EXPERIMENTAL","Each subject receives a single intravenous injection of 18F-FDG and 68Ga-FAPI-LM3, and undergo PET\u002FCT imaging within the specified time.",[13],"Diagnostic Test: 18F-FDG PET\u002FCT, 68Ga-FAPI-LM3 PET\u002FCT",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DIAGNOSTIC_TEST","18F-FDG PET\u002FCT, 68Ga-FAPI-LM3 PET\u002FCT","Each subject receives a single intravenous injection of 18F-FDG and 68Ga-FAP-LM3, and undergo PET\u002FCT imaging within the specified time. A part of participants will undergo additional 68Ga-FAPI-46 PET\u002FCT for comparison.",[9],null,[22],{"name":23,"affiliation":24,"role":25},"Long Sun, PhD","The First Affiliated Hospital of Xiamen University, Fujian, China","STUDY_DIRECTOR",[27],{"name":23,"role":28,"phone":29,"phoneExt":20,"email":30},"CONTACT","86 0592-2137077","13178352662@163.com",[32],{"facility":5,"status":33,"city":34,"state":35,"zip":36,"country":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"RECRUITING","Xiamen","Fujian","0086-361000","China",{"type":39,"coordinates":40},"Point",[41,42],118.08187,24.47979,{"lat":42,"lon":41},[45,46],{"name":23,"role":28,"phone":29,"phoneExt":20,"email":30},{"name":47,"role":28,"phone":48,"phoneExt":20,"email":49},"Haojun Chen, PhD","86 0592-2137166","leochen0821@foxmail.com",{"type":51,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100506391",false,"NCT05873777","68Ga-FAPI-LM3 PET\u002FCT Imaging in Patients With FAP\u002FSSTR2 Positive Disease and Compared With 18F-FDG","Inclusion Criteria:\n\n* (i) adult patients (aged 18 years or order);\n* (ii) patients with suspected or newly diagnosed or previously malignant disease, with either FAP or SSTR2 positive expression (supporting evidence may include MRI, CT, and pathology report etc);\n* (iii) patients who had scheduled both 18F-FDG and 68Ga-FAPI-LM3 PET\u002FCT scans;\n* (iv) patients who were able to provide informed consent (signed by participant, parent or legal representative) and assent according to the guidelines of the Clinical Research Ethics Committee.\n\nExclusion Criteria:\n\n* (i) patients with non-malignant disease;\n* (ii) patients with pregnancy;\n* (iii) the inability or unwillingness of the research participant, parent or legal representative to provide written informed consent.",true,"ALL","18 Years",{"count":61,"type":62},30,"ESTIMATED","INTERVENTIONAL",[65],"NA","As a new dual receptor (SSTR2 and FAP) targeting PET radiotracer, 68Ga-FAPI-LM3 is promising as an excellent imaging agent applicable to SSTR2 positive diseases. In this research, we investigate the safety, biodistribution and radiation dosimetry of 68Ga-FAPI-LM3 in healthy volunteers. Moreover, we evaluate the potential usefulness of 68Ga-FAPI-LM3 positron emission tomography\u002Fcomputed tomography (PET\u002FCT) for the diagnosis of lesions in SSTR2 positive diseases, and compared with 18F-FDG PET\u002FCT.",[68,69,70],"SSTR2","FAP","Positron-Emission Tomography",[68,69,70],"2025-08-05",{"date":74,"type":75},"2025-08-08","ACTUAL",{"date":77,"type":75},"2023-04-09",{"date":79,"type":62},"2025-12-31",{"name":5,"class":6},1]