Health Trials

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

ConditionsHematologic MalignanciesInherited Disorders of MetabolismInherited Abnormalities of PlateletsHistiocytic DisordersAcute Myelogenous Leukemia (AML or ANLL)Acute Lymphoblastic Leukemia (ALL)Other Acute LeukemiaChronic Myelogenous Leukemia (CML)Myelodysplastic (MDS) / Myeloproliferative (MPN) DiseasesOther LeukemiaHodgkin LymphomaNon-hodgkin LymphomaMultiple Myeloma/ Plasma Cell Disorder (PCD)Inherited Abnormalities of Erythrocyte Differentiation or FunctionDisorders of the Immune SystemAutoimmune DiseasesSevere Aplastic Anemia
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorCenter for International Blood and Marrow Transplant Research

About this trial

This study is an access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) in pediatric and adult patients with hematologic malignancies and other indications.

Eligibility criteria

Qualifiers

Disorders affecting the hematopoietic system that are inherited, acquired, or result from myeloablative treatment

Signed informed consent (and signed assent, if applicable) obtained prior to study enrollment

Pediatric and adult patients of any age

Disqualifiers

Patients who are receiving only licensed CBUs

Cord blood transplant recipients at international transplant centers

Patients who are enrolled on another IND protocol to access the unlicensed CBU(s)

Patients whose selected unlicensed CBU(s) will be more than minimally manipulated

Trial design

Treatments tested in this trial

  • A multicenter access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs)

Treatment groups

99,999 Participants
are divided into 1 treatment group

Locations

142
Alabama
University of Alabama at Birmingham35233, Birmingham United States
Arizona
Banner MD Anderson Cancer Center85234, Gilbert United States
Mayo Clinic Arizona (adults)85054, Phoenix United States
Phoenix Children's Hospital85016, Phoenix United States

Sponsors and collaborators

Center for International Blood and Marrow Transplant Research

Lead sponsor

National Marrow Donor Program

Collaborator

Source ClinicalTrials.gov