[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100556131":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":40,"responsibleParty":53,"collaborators":56,"id":58,"slug":26,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":61,"acronym":26,"eligibilityCriteria":62,"healthyVolunteers":63,"sex":64,"minAge":65,"maxAge":26,"enrollmentInfo":66,"targetDuration":26,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":26,"overallStatus":43,"whyStopped":26,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Education University of Hong Kong","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Evaluative conditioning group with positive stimuli","EXPERIMENTAL","Participants will be exposed to social stimuli paired with positive stimuli across multiple sessions.",[13],"Behavioral: Evaluative Conditioning with positive stimuli",{"label":15,"type":16,"description":17,"interventionNames":18},"Control group with neutral stimuli","ACTIVE_COMPARATOR","Participants will be exposed to social stimuli paired with neutral stimuli across multiple sessions.",[19],"Behavioral: Conditioning with neutral stimuli",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Evaluative Conditioning with positive stimuli","In the pre-conditioning phase, participants will be exposed to pictures that vary in their emotional (negative, positive) and social (non-social, social) content. For each picture, they are required to indicate their immediate perceived valence (between negative to positive), degree of social motivation (between none to high) on Likert-scales. In the conditioning phase, emotional social pictures will be selected and paired with non-social positive stimuli for trials in random order, for 6 sessions across 3 weeks. In the post-conditioning phase, participants will be asked to evaluate the valence of the stimuli again similar to that in pre-conditioning phase.",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Conditioning with neutral stimuli","In the pre-conditioning phase, participants will be exposed to pictures that vary in their emotional (negative, positive) and social (non-social, social) content. For each picture, they are required to indicate their immediate perceived valence (between negative to positive), degree of social motivation (between none to high) on Likert-scales. In the conditioning phase, emotional social pictures will be selected and paired with with neutral non-social stimuli for trials in random order, for 6 sessions across 3 weeks. In the post-conditioning phase, participants will be asked to evaluate the valence of the stimuli again similar to that in pre-conditioning phase.",[15],[32],{"name":33,"affiliation":5,"role":34},"Nichol ML Wong, PhD","PRINCIPAL_INVESTIGATOR",[36],{"name":33,"role":37,"phone":38,"phoneExt":26,"email":39},"CONTACT","852-29487431","nmlwong@eduhk.hk",[41],{"facility":42,"status":43,"city":44,"state":26,"zip":26,"country":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"The University of Hong Kong","RECRUITING","Hong Kong",{"type":46,"coordinates":47},"Point",[48,49],114.17469,22.27832,{"lat":49,"lon":48},[52],{"name":33,"role":37,"phone":38,"phoneExt":26,"email":39},{"type":34,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"WONG Man Lok Nichol","Assistant Professor",[57],{"name":42,"class":6},"100556131",false,"NCT06521099","A Novel Conditioning Approach to Counter Loneliness in Adults","Inclusion Criteria:\n\n* No histories of learning impairment, major psychiatric disorders or neurological disorders other than depression\n* Normal intelligence\n* At least primary school education\n\nExclusion Criteria:\n\n* On medication or treatments within 2 weeks prior to the beginning of the study that would affect the individual's brain, cognitive and affective functions",true,"ALL","18 Years",{"count":67,"type":68},136,"ESTIMATED","INTERVENTIONAL",[71],"NA","This study aims to test the efficacy of a 6-session conditioning paradigm by investigating the conditioning-induced change in the socio-affective processing, loneliness, depressive symptoms, and neural correlates of lonely adults.",[74],"Loneliness","2026-02-27",{"date":77,"type":78},"2026-03-02","ACTUAL",{"date":80,"type":78},"2025-08-19",{"date":82,"type":68},"2026-06",{"name":5,"class":6},1]