[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100414544":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":10,"centralContacts":10,"locations":18,"responsibleParty":60,"collaborators":63,"id":86,"slug":10,"hasResults":87,"nctId":88,"briefTitle":89,"officialTitle":89,"acronym":10,"eligibilityCriteria":90,"healthyVolunteers":87,"sex":91,"minAge":92,"maxAge":10,"enrollmentInfo":93,"targetDuration":96,"studyType":97,"phases":10,"briefSummary":98,"conditions":99,"keywords":101,"overallStatus":21,"whyStopped":10,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},{"fullName":5,"class":6},"Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)","OTHER",[8],{"label":9,"type":10,"description":10,"interventionNames":11},"Personalized surveillance and intervention protocol",null,[12],"Procedure: Personalized surveillance and intervention protocol",[14],{"type":15,"name":9,"description":16,"armGroupLabels":17,"otherNames":10},"PROCEDURE","This study uses one arm. Participants will undergo endoscopic surveillance with intervals between 3-6 months and 5 years, depending on severity of polyposis and performed endoscopic interventions.",[9],[19,41],{"facility":20,"status":21,"city":22,"state":23,"zip":24,"country":25,"cosmosGeoPoint":26,"geoPoint":31,"contacts":32},"MD Anderson","RECRUITING","Houston","Texas","77030","United States",{"type":27,"coordinates":28},"Point",[29,30],-95.36327,29.76328,{"lat":30,"lon":29},[33,38],{"name":34,"role":35,"phone":36,"phoneExt":10,"email":37},"Annie Lincoln","CONTACT","+1 919 923 4430","aglincoln@mdanderson.org",{"name":39,"role":40,"phone":10,"phoneExt":10,"email":10},"Luigi Ricciardiello","PRINCIPAL_INVESTIGATOR",{"facility":42,"status":21,"city":43,"state":44,"zip":45,"country":46,"cosmosGeoPoint":47,"geoPoint":51,"contacts":52},"Academic Medical Centre","Amsterdam","North Holland","1105AZ","Netherlands",{"type":27,"coordinates":48},[49,50],4.88969,52.37403,{"lat":50,"lon":49},[53,57],{"name":54,"role":35,"phone":55,"phoneExt":10,"email":56},"Evelien Dekker, MD, PhD","0031205661260","e.dekker@amc.uva.nl",{"name":58,"role":59,"phone":10,"phoneExt":10,"email":10},"Arthur Aelvoet, MD","SUB_INVESTIGATOR",{"type":40,"investigatorFullName":61,"investigatorTitle":62,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Prof. Evelien Dekker, MD, PhD","Prof. dr. Evelien Dekker, MD, PhD",[64,66,68,70,72,74,76,78,80,82,84],{"name":65,"class":6},"Leiden University Medical Center",{"name":67,"class":6},"The Netherlands Cancer Institute",{"name":69,"class":6},"St Mark's Hospital Foundation",{"name":71,"class":6},"Hospital Clinic of Barcelona",{"name":73,"class":6},"Maria Sklodowska-Curie National Research Institute of Oncology",{"name":75,"class":6},"Hospital General Universitario de Alicante",{"name":77,"class":6},"IRCCS Azienda Ospedaliero-Universitaria di Bologna",{"name":79,"class":6},"Radboud University Medical Center",{"name":81,"class":6},"University Hospital, Bonn",{"name":83,"class":6},"Hvidovre University Hospital",{"name":85,"class":6},"M.D. Anderson Cancer Center","100414544",false,"NCT04677998","A Personalized Surveillance and Intervention Protocol for Duodenal and Gastric Polyposis in Patients With Familial Adenomatous Polyposis","Inclusion Criteria:\n\n* Diagnosis of FAP, at least one of following: genetic diagnosis (proven APC germline mutation) and\u002For clinical diagnosis (\\>100 colorectal adenomas in combination with a positive family history of FAP)\n* Age 18 years or older\n\nExclusion Criteria:\n\n* Endoscopic removal of all polyps with an indication for removal not possible\u002Ffeasible\n* Gastric or duodenal cancer at baseline endoscopy\n* Need for surgery","ALL","18 Years",{"count":94,"type":95},1000,"ESTIMATED","5 Years","OBSERVATIONAL","The purpose of this study is to determine the efficacy and safety of a personalized surveillance and intervention protocol for duodenal and gastric polyposis in patients with familial adenomatous polyposis (FAP)",[100],"Familial Adenomatous Polyposis",[102,103,104,105],"Endoscopic surveillance","Endoscopic interventions","Personalized care","Gastrointestinal neoplasia","2026-02-20",{"date":108,"type":109},"2026-02-23","ACTUAL",{"date":111,"type":109},"2020-11-24",{"date":113,"type":95},"2027-11",{"name":5,"class":6},2]