[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100585658":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":33,"responsibleParty":62,"collaborators":19,"id":64,"slug":19,"hasResults":65,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":19,"eligibilityCriteria":69,"healthyVolunteers":65,"sex":70,"minAge":71,"maxAge":19,"enrollmentInfo":72,"targetDuration":19,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":81,"overallStatus":51,"whyStopped":19,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"GenieBiome Limited","INDUSTRY",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"MQU10","EXPERIMENTAL","Subjects will take 1 sachet of synbiotics formula (MQU10) daily for 6 weeks",[13],"Dietary Supplement: MQU10",[15],{"type":16,"name":9,"description":17,"armGroupLabels":18,"otherNames":19},"DIETARY_SUPPLEMENT","MQU10 consists of a blend of food-grade probiotic strains (20 billion CFU daily) and prebiotic compounds.",[9],null,[21],{"name":22,"affiliation":5,"role":23},"Jessica Ching, PhD","STUDY_DIRECTOR",[25,30],{"name":26,"role":27,"phone":28,"phoneExt":19,"email":29},"Emily Fung, BSc","CONTACT","(+852) 55024661","emilyfung@g-niib.com",{"name":31,"role":27,"phone":28,"phoneExt":19,"email":32},"Pui Kuan Cheong, MPH","jcheong@g-niib.com",[34,49],{"facility":5,"status":35,"city":36,"state":19,"zip":19,"country":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"NOT_YET_RECRUITING","Hong Kong",{"type":38,"coordinates":39},"Point",[40,41],114.17469,22.27832,{"lat":41,"lon":40},[44,46],{"name":22,"role":27,"phone":28,"phoneExt":19,"email":45},"jessicaching@g-niib.com",{"name":47,"role":48,"phone":19,"phoneExt":19,"email":19},"Ching-Ping Dennis CHEUNG","PRINCIPAL_INVESTIGATOR",{"facility":50,"status":51,"city":36,"state":19,"zip":19,"country":36,"cosmosGeoPoint":52,"geoPoint":54,"contacts":55},"Healthymind Centre","RECRUITING",{"type":38,"coordinates":53},[40,41],{"lat":41,"lon":40},[56,60],{"name":57,"role":27,"phone":58,"phoneExt":19,"email":59},"Moko Cheung, Bsc","9740 5209","mokocheung@g-niib.com",{"name":61,"role":27,"phone":58,"phoneExt":19,"email":45},"Jessica CHING, PhD",{"type":63,"investigatorFullName":19,"investigatorTitle":19,"investigatorAffiliation":19,"oldNameTitle":19,"oldOrganization":19},"SPONSOR","100585658",false,"NCT06905223","A Pilot Study of Synbiotics in Adults With Depressive Symptoms","A Pilot Study on the Efficacy of a Synbiotic Formula (MQU10) in Improving Mood and Well-being in Adults With Mild to Moderate Depressive Symptoms","Inclusion Criteria:\n\n* Individuals aged 18 or above\n* Patient Health Questionnaire-9 (PHQ-9) score between 5 to 14\n* Literate and can complete the self-report questionnaires\n* Able to understand the consent and sign the informed consent form\n\nExclusion Criteria:\n\n* Current diagnosis of substance abuse or dependence;\n* A current or past history of bipolar disorder, manic or hypomanic episodes, schizophrenia, personality disorder, posttraumatic stress disorder (PTSD), intellectual disability, neurodegenerative disorders (e. g, Parkinson's disease) or organic mental disorder\n* Requiring immediate psychiatric care (e. g, imminently suicidal subjects) or have attempted suicide in the past 3 months\n* Use of antipsychotics, antidepressants or sedatives, unless on a stable dose in the last 4 weeks\n* History of severe organ failure, renal failure on dialysis, HIV infection\n* Active malignancy within 5 years\n* History of major surgery on the gastrointestinal tract, except cholecystectomy and appendectomy in the past 5 years\n* Night shift work\n* History of antibiotic use within 4 weeks\n* History of allergy to probiotics or lactose leading to a severe allergic reaction\n* Known pregnancy or lactating","ALL","18 Years",{"count":73,"type":74},30,"ESTIMATED","INTERVENTIONAL",[77],"NA","This study aims to explore the efficacy and safety of a synbiotic formula (MQU10) in improving mood and well-being in adults with mild to moderate depressive symptoms.",[80],"Depressive Symptoms Mild to Moderate in Severity",[82,83,84],"Depressive symptoms","Synbiotics","Adult Mood","2025-06-04",{"date":87,"type":88},"2025-06-08","ACTUAL",{"date":90,"type":88},"2025-04-03",{"date":92,"type":74},"2027-09-26",{"name":5,"class":6},2]