[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100629807":3},{"organization":4,"outcomesModule":7,"designInfo":28,"detailedDescription":31,"studyPopulation":32,"armGroups":33,"interventions":38,"overallOfficials":27,"centralContacts":43,"locations":49,"responsibleParty":183,"collaborators":27,"id":185,"slug":27,"hasResults":186,"nctId":187,"briefTitle":188,"officialTitle":189,"acronym":190,"eligibilityCriteria":191,"healthyVolunteers":186,"sex":192,"minAge":193,"maxAge":194,"enrollmentInfo":195,"targetDuration":27,"studyType":198,"phases":27,"briefSummary":199,"conditions":200,"keywords":27,"overallStatus":202,"whyStopped":27,"lastUpdateSubmitDate":203,"lastUpdatePostDateStruct":204,"startDateStruct":207,"completionDateStruct":209,"leadSponsor":211,"locationsCount":212},{"fullName":5,"class":6},"Gruppo Oncologico Italiano di Ricerca Clinica","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":27},[9],{"measure":10,"description":11,"timeFrame":12},"Primary outcome","Describe clinical and tumor features of newly diagnosed EoGI cancer patients in a real-world Italian setting.","One year from the enrollment",[14,18,22,25],{"measure":15,"description":16,"timeFrame":17},"Secondary outcome measure","EoGI cancer type of treatment at diagnosis (chemotherapy, immunotherapy, targeted therapy, surgery, radiotherapy or best supportive care); progression of disease (if any) and survival status at 6 and 12 months follow-up.","Six and twelve months follow-up",{"measure":19,"description":20,"timeFrame":21},"Secondary Outcome","Incidence and prevalence of newly diagnosed EoGI cancer at each participating site during the study accrual time period","Two years",{"measure":19,"description":23,"timeFrame":24},"Description of patients' lifetime exposure to behavioral and cancer-related risk factors","One years from enrollment",{"measure":19,"description":26,"timeFrame":24},"Identify associations between past lifestyle habits (diet, physical activity, smoking, alcohol consumption,) and tumor-related features (stage, histology, anatomical site, and molecular markers) in EoGI cancer patients",null,{"allocation":27,"interventionModel":27,"interventionModelDescription":27,"primaryPurpose":27,"observationalModel":29,"timePerspective":30,"maskingInfo":27},"COHORT","PROSPECTIVE","This is an observational, prospective multicenter study to characterize newly diagnosed EoGI cancer patients from a holistic approach, covering aspects from tumor features to patient lifestyle habits. Since this is a prospective observational study, participation does not alter any cancer treatments that patients will undergo after their cancer diagnosis, as per best clinical practice at each participating center. The number of patients included in the study will range from 150 to 200, enrolled in national centers located in northern Italy, as well as in diverse hospital settings (e.g., small vs. large hospitals).","Patients will be selected and recruited during routine medical appointments by specialized medical oncologists at the participating cancer center. Patients will be enrolled consecutively based on inclusion and exclusion criteria",[34],{"label":35,"type":27,"description":27,"interventionNames":36},"EoGI cancer patients newly diagnosed",[37],"Other: to characterize the distinctive features of EO-GI cancer through a comprehensive approach that considers clinical and demographic factors, tumor features, and patient lifestyle habits",[39],{"type":6,"name":40,"description":41,"armGroupLabels":42,"otherNames":27},"to characterize the distinctive features of EO-GI cancer through a comprehensive approach that considers clinical and demographic factors, tumor features, and patient lifestyle habits","to characterize the distinctive features of EO-GI cancer through a comprehensive approach that considers clinical and demographic factors, tumor features, and patient lifestyle habits, in a real-world Italian settings, mainly located in Northern Italy",[35],[44],{"name":45,"role":46,"phone":47,"phoneExt":27,"email":48},"Ilaria Bernardini, MD","CONTACT","+39 059659294","i.bernardini@ausl.mo.it",[50,65,77,89,101,112,123,135,147,159,171],{"facility":51,"status":27,"city":52,"state":53,"zip":27,"country":54,"countryCode":55,"cosmosGeoPoint":56,"geoPoint":61,"contacts":62},"Oncologia, Ospedale Sant'Orsola","Bologna","BO","Italy","IT",{"type":57,"coordinates":58},"Point",[59,60],11.33875,44.49381,{"lat":60,"lon":59},[63],{"name":64,"role":46,"phone":27,"phoneExt":27,"email":27},"Karim Rihawi, MD",{"facility":66,"status":27,"city":67,"state":68,"zip":27,"country":54,"countryCode":55,"cosmosGeoPoint":69,"geoPoint":73,"contacts":74},"Istituto Romagnolo per lo studio dei tumori \"Dino Amadori\", IRCCS IRST","Meldola","FC",{"type":57,"coordinates":70},[71,72],12.0626,44.12775,{"lat":72,"lon":71},[75],{"name":76,"role":46,"phone":27,"phoneExt":27,"email":27},"Ilario Rasparelli, MD",{"facility":78,"status":27,"city":79,"state":80,"zip":27,"country":54,"countryCode":55,"cosmosGeoPoint":81,"geoPoint":85,"contacts":86},"Oncologia Ospedale Carlo Poma di Mantova","Mantua","MN",{"type":57,"coordinates":82},[83,84],10.79784,45.16031,{"lat":84,"lon":83},[87],{"name":88,"role":46,"phone":27,"phoneExt":27,"email":27},"Francesca Turina, MD",{"facility":90,"status":27,"city":91,"state":92,"zip":27,"country":54,"countryCode":55,"cosmosGeoPoint":93,"geoPoint":97,"contacts":98},"Oncologia di Prossimità, Ospedale di Carpi e DHO Mirandola, Ausl Modena","Carpi","MO",{"type":57,"coordinates":94},[95,96],10.8777,44.78237,{"lat":96,"lon":95},[99],{"name":100,"role":46,"phone":27,"phoneExt":27,"email":27},"Claudia Mucciarini, MD",{"facility":102,"status":27,"city":103,"state":92,"zip":27,"country":54,"countryCode":55,"cosmosGeoPoint":104,"geoPoint":108,"contacts":109},"Centro Oncologico Modenese, Azienda Policlinico Universitaria di Modena","Modena",{"type":57,"coordinates":105},[106,107],10.92539,44.64783,{"lat":107,"lon":106},[110],{"name":111,"role":46,"phone":27,"phoneExt":27,"email":27},"Alessandro Spallanzani, MD",{"facility":113,"status":27,"city":114,"state":92,"zip":27,"country":54,"countryCode":55,"cosmosGeoPoint":115,"geoPoint":119,"contacts":120},"Oncologia Area Sud Ausl Modena","Sassuolo",{"type":57,"coordinates":116},[117,118],10.7848,44.5432,{"lat":118,"lon":117},[121],{"name":122,"role":46,"phone":27,"phoneExt":27,"email":27},"Teresa Zielli, MD",{"facility":124,"status":27,"city":125,"state":126,"zip":27,"country":54,"countryCode":55,"cosmosGeoPoint":127,"geoPoint":131,"contacts":132},"Oncologia Medica, AUSL Piacenza","Piacenza","PC",{"type":57,"coordinates":128},[129,130],9.69342,45.05242,{"lat":130,"lon":129},[133],{"name":134,"role":46,"phone":27,"phoneExt":27,"email":27},"Margherita Ratti, MD",{"facility":136,"status":27,"city":137,"state":138,"zip":27,"country":54,"countryCode":55,"cosmosGeoPoint":139,"geoPoint":143,"contacts":144},"Oncologia, Azienda Ospedaliero Universitaria di Parma","Parma","PR",{"type":57,"coordinates":140},[141,142],10.32618,44.79935,{"lat":142,"lon":141},[145],{"name":146,"role":46,"phone":27,"phoneExt":27,"email":27},"Annalisa Gilli, MD",{"facility":148,"status":27,"city":149,"state":150,"zip":27,"country":54,"countryCode":55,"cosmosGeoPoint":151,"geoPoint":155,"contacts":156},"Oncologia Medica, CORE Azienda USL-IRCCS Reggio Emilia","Reggio Emilia","RE",{"type":57,"coordinates":152},[153,154],10.63125,44.69825,{"lat":154,"lon":153},[157],{"name":158,"role":46,"phone":27,"phoneExt":27,"email":27},"Francesco Caputo, MD",{"facility":160,"status":27,"city":161,"state":162,"zip":27,"country":54,"countryCode":55,"cosmosGeoPoint":163,"geoPoint":167,"contacts":168},"Oncologia, Ospedale di Rimini","Rimini","RN",{"type":57,"coordinates":164},[165,166],12.56528,44.05755,{"lat":166,"lon":165},[169],{"name":170,"role":46,"phone":27,"phoneExt":27,"email":27},"Francesca Fabbri, MD",{"facility":172,"status":27,"city":173,"state":174,"zip":27,"country":54,"countryCode":55,"cosmosGeoPoint":175,"geoPoint":179,"contacts":180},"Oncologia, ASST SETTE LAGHI, Ospedale di Circolo","Varese","VA",{"type":57,"coordinates":176},[177,178],8.82511,45.82058,{"lat":178,"lon":177},[181],{"name":182,"role":46,"phone":27,"phoneExt":27,"email":27},"Michele Ghidini, MD",{"type":184,"investigatorFullName":27,"investigatorTitle":27,"investigatorAffiliation":27,"oldNameTitle":27,"oldOrganization":27},"SPONSOR","100629807",false,"NCT07479472","A Prospective Observational Study on of Early-Onset Gastrointestinal Cancer: From Tumor Features to Patient Lifestyle Habits","A Prospective Observational Study on of Early-Onset Gastrointestinal Cancer: From Tumor Features to Patient Lifestyle Habits - YOGICO Study","YOGICO","Inclusion Criteria:\n\n* Provide a signed and dated informed consent form (ICF)\n* Willing to comply with all study procedures and be available for the duration of the study\n* Male or female, aged 18-49 years old at time of EoGI cancer diagnosis\n* Patients with newly diagnosed early-onset gastrointestinal cancer histologically confirmed: colorectal, gastroesophageal and pancreatic tumor site, regardless of histological type\n* Any disease stage, performance status, and type of treatment, including experimental therapies and supportive care\n* Previous or concomitant malignancies are allowed provided they do not involve the gastrointestinal tract\n\nExclusion Criteria:\n\n* Cognitive, linguistic, or physical barriers that prevent a detailed reconstruction of the patient's personal medical history including past lifestyle habits\n* Having previously received any treatments directed at the newly diagnosed EOGI cancer (i.e., at the time of inclusion, the patient has not yet started any type of treatment, excluding surgery)","ALL","18 Years","49 Years",{"count":196,"type":197},150,"ESTIMATED","OBSERVATIONAL","The YOGICO study aims to characterize the distinctive features of EoGI cancer through a holistic approach that integrates clinical and demographic data, tumor biological characteristics, and patient lifestyle habits",[201],"Early-onset Gastrointestinal Cancer","NOT_YET_RECRUITING","2026-03-13",{"date":205,"type":206},"2026-03-18","ACTUAL",{"date":208,"type":197},"2026-04",{"date":210,"type":197},"2028-04",{"name":5,"class":6},11]