[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635910":3},{"organization":4,"outcomesModule":7,"designInfo":54,"detailedDescription":53,"studyPopulation":53,"armGroups":60,"interventions":73,"overallOfficials":83,"centralContacts":87,"locations":93,"responsibleParty":108,"collaborators":110,"id":114,"slug":53,"hasResults":115,"nctId":116,"briefTitle":117,"officialTitle":118,"acronym":53,"eligibilityCriteria":119,"healthyVolunteers":115,"sex":120,"minAge":121,"maxAge":53,"enrollmentInfo":122,"targetDuration":53,"studyType":125,"phases":126,"briefSummary":128,"conditions":129,"keywords":131,"overallStatus":137,"whyStopped":53,"lastUpdateSubmitDate":138,"lastUpdatePostDateStruct":139,"startDateStruct":142,"completionDateStruct":144,"leadSponsor":146,"locationsCount":147},{"fullName":5,"class":6},"University of South Florida","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":22,"otherOutcomes":53},[9,13,16,19],{"measure":10,"description":11,"timeFrame":12},"Phobia symptom severity","The Severity Measure for Specific Phobia (SMSP) is a 10-item self-report questionnaire that assesses the severity of specific phobia symptoms relative to an individual's feared stimulus. Total scores range from 0 to 4 with higher scores indicating higher phobia severity.","Baseline, 4 Weeks Post-Baseline (Mid-Treatment), 7 Weeks Post-Baseline (Post-Treatment), and 28 weeks Post-Baseline (3-Months Post-Treatment)",{"measure":14,"description":15,"timeFrame":12},"Dog Phobia Severity","The Dog Phobia Questionnaire (DPQ) is a 27-item, self-report questionnaire assessing the severity of dog phobia symptoms. Scores range from 27 to 189 with higher scores indicating higher phobia severity.",{"measure":17,"description":18,"timeFrame":12},"Snake Phobia Severity","The Snake Anxiety Questionnaire (SNAQ) is a 30-item self-report questionnaire assessing the severity of snake phobia symptoms. Scores range from 0 to 30 with higher scores indicating higher phobia severity.",{"measure":20,"description":21,"timeFrame":12},"Spider Phobia Severity","The Fear of Spiders Questionnaire (FSQ) is an 18-item self-report questionnaire assessing the severity of spider phobia symptoms. Scores range from 18 to 126 with higher scores indicating higher phobia severity.",[23,26,30,33,36,40,43,47,50],{"measure":24,"description":25,"timeFrame":12},"Specific Phobia Diagnosis","The Diagnostic Assessment Research Tool (DART) is a modular semi structured interview corresponding with the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5). Study therapists administer the DART Specific Phobia Module, which provides designations of Absent, Subthreshold, and Present.",{"measure":27,"description":28,"timeFrame":29},"General Anxiety","The Generalized Anxiety Disorder-7 (GAD-7) is a 7-item self-report measure of anxiety symptom severity. Scores range from 0 to 15 with higher scores indicating higher anxiety severity.","Baseline, 7 Weeks Post-Baseline (Post-Treatment), and 28 weeks Post-Baseline (3-Months Post-Treatment)",{"measure":31,"description":32,"timeFrame":29},"Depression Severity","The Patient Health Questionnaire-8 (PHQ-8) is an 8-item self-report measure of depression symptom severity. Scores range from 0 to 27 with higher scores indicating higher depression severity.",{"measure":34,"description":35,"timeFrame":29},"Quality of Life Level","The Quality of Life Scale (QOLS) is a 16-item self-report measure of quality of life. Scores range from 16 to 112 with higher scores indicating better quality of life.",{"measure":37,"description":38,"timeFrame":39},"Level of Telepresence","The iGroup Presence Questionnaire (iPQ) is a 14-item self-report questionnaire of telepresence. Scores on each subscale range from 0-6 with higher scores indicating more presence.","Week 1, Week 2, Week 3, Week 4, Week 5, Week 6, Week 7; Averaged across weeks",{"measure":41,"description":42,"timeFrame":39},"Cybersickness Severity","The Cybersickness in Virtual Reality Questionnaire (CSQ-VR) is an 6-item measure of nausea, vestibular, and oculomotor cybersickness experienced in virtual reality. Scores range from 6 to 27 with higher scores indicating higher levels of cybersickness.",{"measure":44,"description":45,"timeFrame":46},"Level of Working (Therapeutic) Alliance","The Working Alliance Inventory (WAI-SR) is a 12-item client-rated measure of therapeutic alliance. Total scores range from 1 to 5 with higher scores indicating a better therapeutic alliance.","4 Weeks Post-Baseline (Mid-Treatment), 7 Weeks Post-Baseline (Post-Treatment)",{"measure":48,"description":49,"timeFrame":46},"Satisfaction with Therapy","The Satisfaction with Therapy and Therapist Scale-Revised (STTS-R) is a 13-item self-report questionnaire that assesses client satisfaction with treatment. Scores range from 0 to 60 with higher scores indicating higher satisfaction.",{"measure":51,"description":52,"timeFrame":46},"System Usability","The System Usability Scale (SUS) is a 10-item self-report measure of the usability of a particular software system, platform, or app. Scores range from 0-100 with higher scores indicating better usability.",null,{"allocation":55,"interventionModel":56,"interventionModelDescription":53,"primaryPurpose":57,"observationalModel":53,"timePerspective":53,"maskingInfo":58},"RANDOMIZED","PARALLEL","TREATMENT",{"masking":59,"maskingDescription":53,"whoMasked":53},"NONE",[61,67],{"label":62,"type":63,"description":64,"interventionNames":65},"Telemedicine-based Virtual Reality Exposure Therapy","EXPERIMENTAL","This group will receive exposure therapy in a telemedicine-based Virtual Reality Clinic using virtual reality snakes, dogs, or spiders. The VR stimuli range from small to medium to large and have four activity levels: idle, calm, energetic, and aggressive.",[66],"Behavioral: Telemedicine-Based Virtual Reality Exposure Therapy",{"label":68,"type":69,"description":70,"interventionNames":71},"Standard Telemedicine-Based Exposure Therapy","ACTIVE_COMPARATOR","This group will receive exposure therapy via Doxy.me telemedicine platform using photos and videos of snakes, dogs, or spiders. The photo\u002Fvideo stimuli range from small to medium to large and have four activity levels: idle, calm, energetic, and aggressive.",[72],"Behavioral: Telemedicine-Based Exposure Therapy Using Photos and Videos",[74,79],{"type":75,"name":76,"description":77,"armGroupLabels":78,"otherNames":53},"BEHAVIORAL","Telemedicine-Based Virtual Reality Exposure Therapy","Participants will complete 7 60-minute exposure therapy sessions in a Virtual Reality Clinic using Virtual Reality stimuli and progress to in vivo exposures.\n\nOther Name:",[62],{"type":75,"name":80,"description":81,"armGroupLabels":82,"otherNames":53},"Telemedicine-Based Exposure Therapy Using Photos and Videos","Participants will complete 7 60-minute exposure therapy sessions using photos\u002Fvideos and progress to in vivo exposures.",[68],[84],{"name":85,"affiliation":5,"role":86},"Brian E. Bunnell, PhD","PRINCIPAL_INVESTIGATOR",[88],{"name":89,"role":90,"phone":91,"phoneExt":53,"email":92},"Maureen Jacobs Plaisimond","CONTACT","813-396-0060","MCOM-VRStudy@usf.edu",[94],{"facility":5,"status":53,"city":95,"state":96,"zip":97,"country":98,"countryCode":99,"cosmosGeoPoint":100,"geoPoint":105,"contacts":106},"Tampa","Florida","33613","United States","US",{"type":101,"coordinates":102},"Point",[103,104],-82.45843,27.94752,{"lat":104,"lon":103},[107],{"name":89,"role":90,"phone":91,"phoneExt":53,"email":92},{"type":109,"investigatorFullName":53,"investigatorTitle":53,"investigatorAffiliation":53,"oldNameTitle":53,"oldOrganization":53},"SPONSOR",[111],{"name":112,"class":113},"National Institute of Mental Health (NIMH)","NIH","100635910",false,"NCT07558824","A Randomized Controlled Efficacy Trial of a Telemedicine-based Virtual Reality Clinic for the Treatment of Phobias","Doxy.me VR vs. Telemental Health-Based Exposure Therapy: Phase II","Inclusion Criteria:\n\nIndividuals will be eligible if they: (1) are an adult (≥18 years old); (2) have a self-reported fear of dogs, snakes, and\u002For spiders; (3) score 89 ≥ on the FSQ OR 24 ≥ on the SNAQ OR 147 ≥ on the DPQ; and (4) have access to the internet AND a computer OR smartphone with video conferencing capabilities.\n\nExclusion Criteria:\n\nIndividuals will be ineligible to participate if they: (1) are participating in ongoing mental health therapy from a non-study therapist; (2) changed psychiatric medication use within the past 6 weeks; (3) report active auditory, visual, and\u002For tactile hallucinations via the DART Psychosis Module screening question; (4) report active health conditions requiring upcoming planned or likely hospitalization or intensive treatment that will prevent them from participating; (5) report active legal proceedings that might lead to incarceration during the study period that would prevent them from participating; (6) report an unstable housing situation (eg., eviction or homelessness); (7) have experienced photosensitive seizures within the prior 6 months; (8) endorse more than 20% of symptom validity questions.","ALL","18 Years",{"count":123,"type":124},240,"ESTIMATED","INTERVENTIONAL",[127],"NA","The goal of this clinical trial is to learn if a telemedicine-based virtual reality clinic (Doxy.me VR) works to treat dog, spider, and snake phobias in adults. The main questions it aims to answer are:\n\nDoes Doxy.me VR decrease the severity of phobias better than traditional telemedicine-based treatment? Does this work because it feels more realistic than telemedicine alone?",[130],"Specific Phobia, Animal",[132,133,134,135,136],"phobia","phobias","snakes","dogs","spiders","NOT_YET_RECRUITING","2026-04-23",{"date":140,"type":141},"2026-04-30","ACTUAL",{"date":143,"type":124},"2026-04",{"date":145,"type":124},"2028-01",{"name":5,"class":6},1]