[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100546544":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":38,"locations":45,"responsibleParty":131,"collaborators":25,"id":135,"slug":25,"hasResults":136,"nctId":137,"briefTitle":138,"officialTitle":139,"acronym":140,"eligibilityCriteria":141,"healthyVolunteers":136,"sex":142,"minAge":143,"maxAge":144,"enrollmentInfo":145,"targetDuration":25,"studyType":148,"phases":149,"briefSummary":151,"conditions":152,"keywords":154,"overallStatus":48,"whyStopped":25,"lastUpdateSubmitDate":160,"lastUpdatePostDateStruct":161,"startDateStruct":164,"completionDateStruct":166,"leadSponsor":168,"locationsCount":169},{"fullName":5,"class":6},"McGill University Health Centre\u002FResearch Institute of the McGill University Health Centre","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Exergaming Intervention for 8 Weeks","EXPERIMENTAL","Extension Phase: Participants randomized ot the intervention arm will play Tales from the Magic Keep at home for the 8 week open-label extension phase",[13],"Other: Tales from the Magic Keep™",{"label":15,"type":16,"description":17,"interventionNames":18},"Usual Care for 8 weeks.","ACTIVE_COMPARATOR","Extension Phase: Participants randomized to waitlist usual care will play Tales from the Magic Keep at home for the 8 week open-label extension phase",[19],"Other: Usual Care",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"Tales from the Magic Keep™","Exergame targeting upper limb and trunk movement designed for use on the Microsoft Azure Kinect Dose: At least 3 times a week for 20 minutes over 8 weeks (8 hours total) Continue with regularly accessed physical activities and rehabilitation services",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Usual Care","Continue with regularly accessed physical activities and rehabilitation services",[15],[31,35],{"name":32,"affiliation":33,"role":34},"Maryam Oskoui","McGill University","PRINCIPAL_INVESTIGATOR",{"name":36,"affiliation":37,"role":34},"Danielle Levac","Université de Montréal",[39],{"name":40,"role":41,"phone":42,"phoneExt":43,"email":44},"Mbaye Ndiaye","CONTACT","5149341934","37299","mbaye.ndiaye@muhc.mcgill.ca",[46,66,82,98,115],{"facility":47,"status":48,"city":49,"state":50,"zip":25,"country":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Alberta Children's Hospital","RECRUITING","Calgary","Alberta","Canada",{"type":53,"coordinates":54},"Point",[55,56],-114.08529,51.05011,{"lat":56,"lon":55},[59,64],{"name":60,"role":41,"phone":61,"phoneExt":62,"email":63},"Julie Dao","403-955-7211","7132","Julie.dao@ucalgary.ca",{"name":65,"role":34,"phone":25,"phoneExt":25,"email":25},"Jean Mah",{"facility":67,"status":48,"city":68,"state":69,"zip":25,"country":51,"cosmosGeoPoint":70,"geoPoint":74,"contacts":75},"BC Children's Hospital","Vancouver","British Columbia",{"type":53,"coordinates":71},[72,73],-123.11934,49.24966,{"lat":73,"lon":72},[76,80],{"name":77,"role":41,"phone":78,"phoneExt":62,"email":79},"Alex Salvarinov","604 875 2345","alex.salvarinov@cw.bc.ca",{"name":81,"role":34,"phone":25,"phoneExt":25,"email":25},"Kathryn Selby",{"facility":83,"status":48,"city":84,"state":85,"zip":25,"country":51,"cosmosGeoPoint":86,"geoPoint":90,"contacts":91},"IWK Health Services","Halifax","Nova Scotia",{"type":53,"coordinates":87},[88,89],-63.57688,44.64269,{"lat":89,"lon":88},[92,96],{"name":93,"role":41,"phone":94,"phoneExt":25,"email":95},"Sara Drisdelle","902-789-1599","sara.drisdelle@iwk.nshealth.ca",{"name":97,"role":34,"phone":25,"phoneExt":25,"email":25},"Jordan Sheriko",{"facility":99,"status":48,"city":100,"state":101,"zip":25,"country":51,"cosmosGeoPoint":102,"geoPoint":106,"contacts":107},"Hospital for SickKids","Toronto","Ontario",{"type":53,"coordinates":103},[104,105],-79.39864,43.70643,{"lat":105,"lon":104},[108,113],{"name":109,"role":41,"phone":110,"phoneExt":111,"email":112},"Ana Stosic","416-813-7654","309965","ana.stosic@sickkids.ca",{"name":114,"role":34,"phone":25,"phoneExt":25,"email":25},"Hernan Gonorazky",{"facility":116,"status":48,"city":117,"state":118,"zip":25,"country":51,"cosmosGeoPoint":119,"geoPoint":123,"contacts":124},"Centre de readaptation Marie-Enfant","Montreal","Quebec",{"type":53,"coordinates":120},[121,122],-73.58781,45.50884,{"lat":122,"lon":121},[125,130],{"name":126,"role":41,"phone":127,"phoneExt":128,"email":129},"Evemie Dube","514 374-1710","8601","evemie.dube.hsj@ssss.gouv.qc.ca",{"name":36,"role":34,"phone":25,"phoneExt":25,"email":25},{"type":132,"investigatorFullName":133,"investigatorTitle":134,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"SPONSOR_INVESTIGATOR","Maryam Oskoui, MD, MSc, FRCPC, FAAN","Full Professor, Department of Pediatrics and Neurology & Neurosurgery","100546544",false,"NCT06396325","A Registry Based Randomized-Controlled Trial of an Upper Limb Exergaming Intervention for Children and Adolescents With Spinal Muscular Atrophy","A Registry-Based Parallel Group Randomized-Controlled Trial of an Upper Limb Exergaming Intervention for Children and Adolescents With Spinal Muscular Atrophy, With an Optional Open-Label Extension","INFORM SMA","Inclusion Criteria:\n\n* Confirmed genetic diagnosis of 5q SMA\n* Age at screening: Aged 8-18 years old\n* Participant is able to stay seated independently without support for at least 10 seconds\n* Participants has a score of at least 2 points in entry item A of the RULM (i.e., \"Can raise 1 or 2 hands to the mouth but cannot raise a 200 g weight in it to the mouth\")\n* Treated with disease-modifying therapy\n* Signed ICF\n\nExclusion Criteria:\n\n* Inability to comply with study procedures according to the site investigator, prior to randomization\n* Severe scoliosis or contractures that would interfere with gameplay or with successful completion of functional assessments, as confirmed by the clinical evaluator\n* Planned orthopedic surgery 6 months prior to or throughout intervention and follow-up period (16 weeks post randomization)\n* Inability to read in English or French","ALL","8 Years","18 Years",{"count":146,"type":147},22,"ESTIMATED","INTERVENTIONAL",[150],"NA","This is a multisite randomized controlled registry-based trial to evaluate the efficacy of an 8-week home-based exergaming intervention as compared to usual care on occupational satisfaction of children and youth (8-18 years old age) with spinal muscular atrophy (SMA).",[153],"Spinal Muscular Atrophy",[155,156,157,158,159],"spinal muscular atrophy","rehabilitation","Exergaming","Pediatrics","Randomized-controlled trial","2025-07-03",{"date":162,"type":163},"2025-07-08","ACTUAL",{"date":165,"type":163},"2024-11-01",{"date":167,"type":147},"2027-12-31",{"name":133,"class":6},5]