[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100557198":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":20,"locations":21,"responsibleParty":38,"collaborators":20,"id":42,"slug":20,"hasResults":43,"nctId":44,"briefTitle":45,"officialTitle":45,"acronym":20,"eligibilityCriteria":46,"healthyVolunteers":43,"sex":47,"minAge":48,"maxAge":20,"enrollmentInfo":49,"targetDuration":20,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":23,"whyStopped":20,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":69},{"fullName":5,"class":6},"Hong Kong Baptist University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Treatment group","EXPERIMENTAL","During the 2-week intervention, all participants are required to take 150ml of SCD-2101 liquid (a Chinese herbal medicine formula containing four herbs) twice per day",[13],"Drug: SCD-2101",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DRUG","SCD-2101","Tradictional Chinese Medicine formula (SCD-2101)",[9],null,[22],{"facility":5,"status":23,"city":24,"state":20,"zip":20,"country":25,"cosmosGeoPoint":26,"geoPoint":31,"contacts":32},"RECRUITING","Kowloon Tong","Hong Kong",{"type":27,"coordinates":28},"Point",[29,30],114.17969,22.33312,{"lat":30,"lon":29},[33],{"name":34,"role":35,"phone":36,"phoneExt":20,"email":37},"ZhaoXiang Bian, Prof.","CONTACT","85234116521","bzxiang@hkbu.edu.hk",{"type":39,"investigatorFullName":40,"investigatorTitle":41,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"PRINCIPAL_INVESTIGATOR","ZhaoXiang Bian","Professor","100557198",false,"NCT06534996","A Single Arm Pilot Study of the Chinese Herbal Medicine Formula (SCD-2101) for the Functional Constipation in the Elderly","Inclusion Criteria:\n\n* (1) Age ≥ 60 years old (2) Meet the Rome IV diagnostic criteria for functional constipation (3) Complete spontaneous bowel movements ≤ 2 times per week, to be assessed based on a 2-week electronic diary record (CSBMs are defined as the number of times within a 24-hour period that the patient can defecate spontaneously without the use of laxatives or enemas and feels that the stool is completely evacuated) (4) Have colonoscopy results with a diagnosis of no significant abnormalities seen or no more than 3 colorectal polyps, each less than 0.5 cm in size (based on results within the last 5 years before screening) (5) Understand and be able to follow written and oral instructions in Chinese (6) Capable of independently using WhatsApp and an electronic diary, and completing a 2-week electronic diary record during the screening period (7) The subject is informed and voluntarily signs the informed consent form.\n\nExclusion Criteria:\n\n* (1) Secondary constipation (constipation caused by drugs or other diseases); (2) Currently using or requiring continued use of medications that may affect the outcomes of the trial (including but not limited to: antibiotics, hormonal drugs, analgesics, neurotransmitter drugs, gut flora-regulating medications, etc.); (3) Colonoscopy or sigmoidoscopy reveals clinically significant abnormalities; (4) Clinically significant abnormalities in laboratory tests or imaging examinations within the last 6 months; (5) History of allergy to traditional Chinese medicine; (6) History of abdominal surgery within the past year (except for laparoscopic appendectomy); (7) Patients with psychiatric diseases or those requiring the use of psychotropic drugs; (8) Deemed by the researchers as unsuitable to participate in this study for psychological or physical reasons.","ALL","60 Years",{"count":50,"type":51},14,"ESTIMATED","INTERVENTIONAL",[54],"NA","This single-arm, open-label pilot clinical trial will test the hypothesis that SCD-2101, a Chinese herbal medicine formula, will have efficacy in alleviating constipation in elderly individuals with functional constipation. All participants (n=14) will receive 2 weeks of intervention and 2 weeks of follow-up.",[57],"Functional Constipation",[59],"elderly, Chinese Herbal Medicine, Functional Constipation","2024-08-19",{"date":62,"type":63},"2024-08-20","ACTUAL",{"date":65,"type":63},"2024-08-01",{"date":67,"type":51},"2024-11-30",{"name":5,"class":6},1]