[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100538405":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":32,"centralContacts":36,"locations":45,"responsibleParty":120,"collaborators":122,"id":128,"slug":25,"hasResults":129,"nctId":130,"briefTitle":131,"officialTitle":131,"acronym":132,"eligibilityCriteria":133,"healthyVolunteers":129,"sex":134,"minAge":135,"maxAge":136,"enrollmentInfo":137,"targetDuration":25,"studyType":140,"phases":141,"briefSummary":143,"conditions":144,"keywords":146,"overallStatus":85,"whyStopped":25,"lastUpdateSubmitDate":151,"lastUpdatePostDateStruct":152,"startDateStruct":155,"completionDateStruct":157,"leadSponsor":159,"locationsCount":160},{"fullName":5,"class":6},"Children's Hospital Medical Center, Cincinnati","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Active Treatment","ACTIVE_COMPARATOR","SCThrive is a virtual, 8-week, virtual group-based, behavioral self-management intervention that includes daily use of a companion mobile app.",[13],"Behavioral: SCThrive",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Condition","PLACEBO_COMPARATOR","Participants randomized to SCHealthED will receive usual care plus 7 text messages consisting of SCD educational facts to ensure the care is uniform across sites.",[19],"Other: SCHealthED",[21,26],{"type":22,"name":23,"description":11,"armGroupLabels":24,"otherNames":25},"BEHAVIORAL","SCThrive",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":30},"SCHealthED","Standard of care plus 7 SCD educational text messages to ensure education is uniform across sites",[15],[31],"Uniform Standard Care",[33],{"name":34,"affiliation":5,"role":35},"Lori E. Crosby, PsyD","PRINCIPAL_INVESTIGATOR",[37,42],{"name":38,"role":39,"phone":40,"phoneExt":25,"email":41},"Ama Wilson, MPH","CONTACT","15136365380","Ama.Wilson@cchmc.org",{"name":43,"role":39,"phone":25,"phoneExt":25,"email":44},"Taylor Richardson, BA","Taylor.Richardson2@cchmc.org",[46,66,83,103],{"facility":47,"status":48,"city":49,"state":50,"zip":51,"country":52,"cosmosGeoPoint":53,"geoPoint":58,"contacts":59},"Nemours Children's Health","NOT_YET_RECRUITING","Wilmington","Delaware","19803","United States",{"type":54,"coordinates":55},"Point",[56,57],-75.54659,39.74595,{"lat":57,"lon":56},[60,64],{"name":61,"role":39,"phone":62,"phoneExt":25,"email":63},"Benjamin Bear, MSW","302-723-9331","benjamin.bear@nemours.org",{"name":65,"role":35,"phone":25,"phoneExt":25,"email":25},"Aimee Hildenbrand, PhD",{"facility":67,"status":48,"city":68,"state":69,"zip":70,"country":52,"cosmosGeoPoint":71,"geoPoint":75,"contacts":76},"Children's Healthcare of Atlanta","Atlanta","Georgia","30303",{"type":54,"coordinates":72},[73,74],-84.38798,33.749,{"lat":74,"lon":73},[77,81],{"name":78,"role":39,"phone":79,"phoneExt":25,"email":80},"Vontarius Howard","404-785-3245","Vontarius.Howard@choa.org",{"name":82,"role":35,"phone":25,"phoneExt":25,"email":25},"Soumitri Sil, PhD",{"facility":84,"status":85,"city":86,"state":87,"zip":88,"country":52,"cosmosGeoPoint":89,"geoPoint":93,"contacts":94},"Cincinnati Children's Hospital Medical Center","RECRUITING","Cincinnati","Ohio","45229",{"type":54,"coordinates":90},[91,92],-84.51439,39.12711,{"lat":92,"lon":91},[95,99,102],{"name":96,"role":39,"phone":97,"phoneExt":25,"email":98},"Lori Crosby, PsyD","513-636-5380","lori.crosby@cchmc.org",{"name":38,"role":39,"phone":100,"phoneExt":25,"email":101},"513-803-0917","ama.wilson@cchmc.org",{"name":96,"role":35,"phone":25,"phoneExt":25,"email":25},{"facility":104,"status":48,"city":105,"state":106,"zip":107,"country":52,"cosmosGeoPoint":108,"geoPoint":112,"contacts":113},"Children's Hospital of Philadelphia","Philadelphia","Pennsylvania","19104",{"type":54,"coordinates":109},[110,111],-75.16362,39.95238,{"lat":111,"lon":110},[114,118],{"name":115,"role":39,"phone":116,"phoneExt":25,"email":117},"Polina Poliakova","267-426-0355","poliakovap@chop.edu",{"name":119,"role":35,"phone":25,"phoneExt":25,"email":25},"Lisa Schwartz, PhD",{"type":121,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR",[123,125,127],{"name":124,"class":6},"Nemours Children's Health System",{"name":126,"class":6},"Emory University",{"name":104,"class":6},"100538405",false,"NCT06290401","A Socio-ecological Approach for Improving Self-management in Adolescents With SCD","SC-Thrive","Inclusion Criteria:\n\n* Patient of a participating SCD Clinic\n* Confirmed diagnosis of SCD\n* 13-21 years of age\n\nExclusion Criteria:\n\n* Another chronic disease (which would complicate measurement of patient activation)\n* Non-English-speaking\n* Cognitive or psychiatric disorder that the physician or study therapists believe would impair study participation.","ALL","13 Years","21 Years",{"count":138,"type":139},310,"ESTIMATED","INTERVENTIONAL",[142],"NA","The goal of this clinical trial is to evaluate the impact of SCThrive (a behavioral self-management intervention) on patient activation, self-management behaviors, daily functioning, and emergency room visits in 260 adolescents and young adults with sickle cell disease (SCD) ages 13-21 receiving care at 1 of 4 pediatric SCD clinics.\n\nThe main question\\[s\\]it aims to answer are:\n\n* Does SCThrive improve patient activation?\n* Does SCThrive improve self-management behaviors, daily functioning, and decrease emergency room visits?\n* Are any improvements maintained 3 months after treatment?\n\nParticipants will complete self-management related surveys before, after, and 3 months following their participation in an 8- week, virtual group intervention with an accompanying mobile app (SCThrive).\n\nResearchers will compare outcomes for participants who receive SCThrive and participants who receive uniform standard care (SCHealthED which = standard of care plus SCD educational text messages) to see if there are differences in patient activation, self-management behaviors, daily functioning, and emergency room visits.",[145],"Anemia, Sickle Cell",[147,148,149,150],"adolescent and young adult (AYA)","self-management","behavioral intervention","sickle cell disease","2026-05-06",{"date":153,"type":154},"2026-05-11","ACTUAL",{"date":156,"type":154},"2025-02-03",{"date":158,"type":139},"2028-06-30",{"name":5,"class":6},4]