[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100569806":3},{"organization":4,"outcomesModule":7,"designInfo":39,"detailedDescription":52,"studyPopulation":38,"armGroups":53,"interventions":66,"overallOfficials":74,"centralContacts":78,"locations":87,"responsibleParty":107,"collaborators":38,"id":110,"slug":38,"hasResults":111,"nctId":112,"briefTitle":113,"officialTitle":114,"acronym":38,"eligibilityCriteria":115,"healthyVolunteers":111,"sex":116,"minAge":117,"maxAge":118,"enrollmentInfo":119,"targetDuration":38,"studyType":122,"phases":123,"briefSummary":125,"conditions":126,"keywords":128,"overallStatus":90,"whyStopped":38,"lastUpdateSubmitDate":133,"lastUpdatePostDateStruct":134,"startDateStruct":137,"completionDateStruct":139,"leadSponsor":141,"locationsCount":142},{"fullName":5,"class":6},"Hepatopancreatobiliary Surgery Institute of Gansu Province","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":15,"otherOutcomes":38},[9,13],{"measure":10,"description":11,"timeFrame":12},"Number of patients with complete expulsion of gallbladder sludge after three days of intervention","Determined by ultrasound examination before and after the intervention to assess whether gallbladder sludge has been fully expelled","7 days",{"measure":14,"description":11,"timeFrame":12},"2）Number of patients with complete expulsion of gallbladder sludge after six days of intervention",[16,19,22,25,28,32,35],{"measure":17,"description":18,"timeFrame":12},"Gallbladder Volume","Measured by ultrasound (L × W × D × 0.52)",{"measure":20,"description":21,"timeFrame":12},"Gallbladder Wall Thickness","Measured by ultrasound, accurate to 0.1 mm",{"measure":23,"description":24,"timeFrame":12},"Serum bilirubin","Determined by lab examination within 3.4-17.1μmol\u002FL",{"measure":26,"description":27,"timeFrame":12},"Presence of Abdominal Pain Post-Intervention","If abdominal pain is present, it will be assessed using the Numerical Rating Scale (NRS) within 0-10, The higher the score, the more serious it is",{"measure":29,"description":30,"timeFrame":31},"Occurrence of Acute Pancreatitis Post-Intervention","Pain and Amy \\>3times as normal","14 days",{"measure":33,"description":34,"timeFrame":31},"Occurrence of Gastrointestinal Bleeding Post-Intervention","Black stool or decrease of HB",{"measure":36,"description":37,"timeFrame":31},"Nausea, Vomiting, and Diarrhea Post-Intervention","Frequency of Nausea, Vomiting, and Diarrhea Post-Intervention",null,{"allocation":40,"interventionModel":41,"interventionModelDescription":42,"primaryPurpose":43,"observationalModel":38,"timePerspective":38,"maskingInfo":44},"RANDOMIZED","PARALLEL","Parallel Assignment","TREATMENT",{"masking":45,"maskingDescription":46,"whoMasked":47},"QUADRUPLE","Double (Investigator, Participant)",[48,49,50,51],"PARTICIPANT","CARE_PROVIDER","INVESTIGATOR","OUTCOMES_ASSESSOR","Gallstones are a common clinical condition, and their prevalence has been increasing globally in recent years. Gallstone formation is a result of various combined factors, and in its early stages, gallstones often exist in a sludge-like form. Currently, there is no definitive research on whether gallbladder sludge can be effectively expelled through medication or dietary therapy. Therefore, the investigators are conducting a double-blind, prospective, single-center controlled trial to verify whether gallbladder sludge-like stones can be effectively expelled using dietary therapy.",[54,60],{"label":55,"type":56,"description":57,"interventionNames":58},"Functional fatty acids","EXPERIMENTAL","Oral Administration of functional fatty acids",[59],"Drug: Functional fatty acids",{"label":61,"type":62,"description":63,"interventionNames":64},"Placebo","PLACEBO_COMPARATOR","Oral Administration of Placebo",[65],"Other: Placebo",[67,71],{"type":68,"name":55,"description":69,"armGroupLabels":70,"otherNames":38},"DRUG","Days 1-3: Oral Administration of functional fatty acids Days 4-6: Oral Administration of functional fatty acids",[55],{"type":6,"name":61,"description":72,"armGroupLabels":73,"otherNames":38},"Days 1-3: Placebo Days 4-6: Oral Administration of functional fatty acids",[61],[75],{"name":76,"affiliation":5,"role":77},"Wenbo Meng, M.D.","PRINCIPAL_INVESTIGATOR",[79,83],{"name":76,"role":80,"phone":81,"phoneExt":38,"email":82},"CONTACT","13919177177","mengwb@lzu.edu.cn",{"name":84,"role":80,"phone":85,"phoneExt":38,"email":86},"Long Deng, M.D.","13893192432","ldyy_longdengld@lzu.edu.cn",[88],{"facility":89,"status":90,"city":91,"state":92,"zip":93,"country":94,"countryCode":95,"cosmosGeoPoint":96,"geoPoint":101,"contacts":102},"Long Deng","RECRUITING","Lanzhou","Gansu","730000","China","CN",{"type":97,"coordinates":98},"Point",[99,100],103.83987,36.05701,{"lat":100,"lon":99},[103,105],{"name":104,"role":80,"phone":85,"phoneExt":38,"email":86},"Long Deng, M.D,",{"name":106,"role":77,"phone":38,"phoneExt":38,"email":38},"Wenbo Meng, MD,PhD",{"type":77,"investigatorFullName":108,"investigatorTitle":109,"investigatorAffiliation":5,"oldNameTitle":38,"oldOrganization":38},"Wenbo Meng","Director of Surgery","100569806",false,"NCT06699030","A Strategy for Gallstone Expulsion Through Dietary Therapy","A New Strategy for Gallstone Expulsion Through Dietary Therapy: A Prospective, Single-Center, Double-Blind, Randomized Controlled Trial","Inclusion Criteria:\n\n* Gallbladder sludge-like stones with a maximum stone diameter of less than 2 mm\n\nExclusion Criteria:\n\n* History of ERCP (Endoscopic Retrograde Cholangiopancreatography)\n* Previous gallstone removal surgery with gallbladder preservation\n* History of acute or chronic pancreatitis, cholangitis\n* Mirizzi Syndrome\n* History of gastrointestinal surgery\n* Gastrointestinal obstruction\n* Dysfunction of the sphincter of Oddi\n* Gallbladder neck polyps\n* Abnormal gallbladder structure\n* Gallbladder mass\n* Biliary infection or stones\n* Congenital biliary abnormalities\n* Biliary injury or surgery\n* Biliary tumors\n* Gastrointestinal bleeding, liver cirrhosis, or other malignant diseases\n* Significant arrhythmia, bradycardia, or atrioventricular block\n* Severe hypertension, liver or kidney insufficiency\n* Immune, endocrine, hematological, or mental disorders\n* Severe cerebrovascular disease\n* Allergy to relevant foods\n* Pregnant or breastfeeding women\n* Unwillingness or inability to consent to participation","ALL","18 Years","70 Years",{"count":120,"type":121},100,"ESTIMATED","INTERVENTIONAL",[124],"NA","This study is a double-blind, prospective, single-center controlled trial conducted at a tertiary hospital, aiming to determine whether dietary therapy can effectively expel gallstones.",[127],"Gallbladder Stone",[129,130,131,132],"Gallstone","Gallbladder Function","Cholecystitis","Ultrasound Examination","2025-12-24",{"date":135,"type":136},"2025-12-31","ACTUAL",{"date":138,"type":136},"2024-12-24",{"date":140,"type":121},"2026-12-01",{"name":5,"class":6},1]