[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100529820":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":13,"studyPopulation":17,"armGroups":13,"interventions":13,"overallOfficials":18,"centralContacts":22,"locations":31,"responsibleParty":53,"collaborators":13,"id":56,"slug":13,"hasResults":57,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":57,"sex":63,"minAge":64,"maxAge":13,"enrollmentInfo":65,"targetDuration":13,"studyType":68,"phases":13,"briefSummary":69,"conditions":70,"keywords":13,"overallStatus":34,"whyStopped":13,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},{"fullName":5,"class":6},"Mayo Clinic","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"Number of episodes identified by the Artificial Intelligence (AI) algorithm as 1R or greater acute cellular rejection, grade 1 or greater antibody mediated rejection, reduction in LVEF to \u003C50%, or a drop in LVEF >5%","Number of episodes identified by the AI algorithm as 1R or greater acute cellular rejection, grade 1 or greater antibody mediated rejection, reduction in LVEF to \\\u003C50%, or a drop in LVEF \\>5% utilizing electrocardiograms and cardiac ultrasound images\u002Fvideos obtained from point of care ultrasound (POCUS) or echocardiograms.","2 years",null,{"allocation":13,"interventionModel":13,"interventionModelDescription":13,"primaryPurpose":13,"observationalModel":15,"timePerspective":16,"maskingInfo":13},"COHORT","PROSPECTIVE","Post-cardiac transplantation subjects, presenting to the cardiac catheterization laboratories at Mayo Clinic in Rochester, MN for routine surveillance biopsies or for diagnostic biopsies in the setting of clinical concern including rejection and graft dysfunction will be enrolled.",[19],{"name":20,"affiliation":5,"role":21},"Atta Behfar, MD, PhD","PRINCIPAL_INVESTIGATOR",[23,28],{"name":24,"role":25,"phone":26,"phoneExt":13,"email":27},"Alyssa Lokensgard","CONTACT","507-422-5123","lokensgard.alyssa@mayo.edu",{"name":20,"role":25,"phone":29,"phoneExt":13,"email":30},"507-266-0318","Behfar.Atta@mayo.edu",[32],{"facility":33,"status":34,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"Mayo Clinic in Rochester","RECRUITING","Rochester","Minnesota","55905","United States","US",{"type":41,"coordinates":42},"Point",[43,44],-92.4699,44.02163,{"lat":44,"lon":43},[47,51,52],{"name":48,"role":25,"phone":49,"phoneExt":13,"email":50},"Ellie Thein","(507) 266-6519","Thein.Ellie@mayo.edu",{"name":20,"role":25,"phone":29,"phoneExt":13,"email":30},{"name":20,"role":21,"phone":13,"phoneExt":13,"email":13},{"type":21,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":13,"oldOrganization":13},"Atta Behfar MD, PhD","Principal Investigator","100529820",false,"NCT06178744","A Study of AI in Cardiac Transplant in Echocardiographic Analysis (ORACLE)","Outcome Reflection for Immune Mediated Rejection by Utilizing Artificial Intelligence in Cardiac Transplant Patients Through Early and Late Echocardiographic Analysis (ORACLE)","ORACLE","Inclusion Criteria:\n\n* Patients undergoing post-cardiac transplant endomyocardial biopsy, and the ability to provide informed consent and a consent for the study.\n\nExclusion Criteria:\n\n* Refusal of study participation","ALL","18 Years",{"count":66,"type":67},500,"ESTIMATED","OBSERVATIONAL","The purpose of this research is to detect episodes of rejection versus non-rejection after cardiac transplant and the diagnostic accuracy of an Artificial Intelligence (AI) algorithm using the data from an ECG (electrocardiogram) and Cardiac Ultrasound (Echocardiogram and\u002For point of care ultrasound).",[71],"Cardiac Transplant Rejection","2026-06-19",{"date":74,"type":75},"2026-06-24","ACTUAL",{"date":77,"type":75},"2024-04-04",{"date":79,"type":67},"2028-06",{"name":5,"class":6},1]