[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100635623":3},{"organization":4,"armGroups":7,"interventions":30,"overallOfficials":36,"centralContacts":49,"locations":55,"responsibleParty":71,"collaborators":75,"id":81,"slug":36,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":86,"eligibilityCriteria":87,"healthyVolunteers":88,"sex":89,"minAge":90,"maxAge":36,"enrollmentInfo":91,"targetDuration":36,"studyType":94,"phases":95,"briefSummary":97,"conditions":98,"keywords":101,"overallStatus":58,"whyStopped":36,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":115},{"fullName":5,"class":6},"Summit Institute for Development, Indonesia","OTHER",[8,15,22,26],{"label":9,"type":10,"description":11,"interventionNames":12},"Digital Care with Blister","EXPERIMENTAL","Participant will get All Standard Care components, MMS provided in blister packaging, daily automated and personalized WhatsApp reminders, WhatsApp, MMS Consumption reminder, Call center, Personalized education via chatbot and consultations, Gamification and alert system, AI monitoring and prediction",[13,14],"Dietary Supplement: Blister pack","Other: Digital care",{"label":16,"type":17,"description":18,"interventionNames":19},"Standard Care with Bottle","ACTIVE_COMPARATOR","Participant will receive standard ANC and PNC services, regular health promotion and printed material, MMS provided in bottle packaging, and no digital adherence support is provided.",[20,21],"Dietary Supplement: Bottle pack","Other: Standard Care",{"label":23,"type":17,"description":24,"interventionNames":25},"Standard Care with Blister","Participant will receive standard ANC and PNC services, regular health promotion and printed material, MMS provided in blister packaging, no digital adherence support is provided.",[13,21],{"label":27,"type":10,"description":28,"interventionNames":29},"Digital Care with Bottle","Participant will get all standard care components, MMS provided in bottle form, daily automated am personalized WhatsApp reminders, WhatsApp MMS consumption reminder, call center, personalized education via chatbot and consultations, gamification and alert system, AI monitoring and prediction",[20,14],[31,37,41,45],{"type":32,"name":33,"description":34,"armGroupLabels":35,"otherNames":36},"DIETARY_SUPPLEMENT","Bottle pack","Bottle packaging of MMS",[27,16],null,{"type":32,"name":38,"description":39,"armGroupLabels":40,"otherNames":36},"Blister pack","Blister packaging of MMS",[9,23],{"type":6,"name":42,"description":43,"armGroupLabels":44,"otherNames":36},"Standard Care","Standard ANC and PNC services, regular health promotion and printed material",[23,16],{"type":6,"name":46,"description":47,"armGroupLabels":48,"otherNames":36},"Digital care","In addition to standard care, participants get intervention such as: Daily automated and personalized WhatsApp reminders, Whatsapp MMS consumption reminder, call center, personalized education via chatbot and consultations, gamification and alert system, AI monitoring and prediction",[9,27],[50],{"name":51,"role":52,"phone":53,"phoneExt":36,"email":54},"Yuni Dwi Setiyawati, MHID","CONTACT","+6285337006810","yuni.setiyawati@sid-indonesia.org",[56],{"facility":57,"status":58,"city":59,"state":60,"zip":61,"country":62,"cosmosGeoPoint":63,"geoPoint":68,"contacts":69},"Summit Institute for Development","RECRUITING","Mataram","West Nusa Tenggara","83239","Indonesia",{"type":64,"coordinates":65},"Point",[66,67],116.11667,-8.58333,{"lat":67,"lon":66},[70],{"name":51,"role":52,"phone":53,"phoneExt":36,"email":54},{"type":72,"investigatorFullName":73,"investigatorTitle":74,"investigatorAffiliation":5,"oldNameTitle":36,"oldOrganization":36},"PRINCIPAL_INVESTIGATOR","Yuni Dwi Setiyawati","Chief Executive Officer",[76,78],{"name":77,"class":6},"Children's Investment Fund Foundation",{"name":79,"class":80},"Sight and Life Foundation","UNKNOWN","100635623",false,"NCT07555093","A Study of Multiple Micronutrient Supplementation (MMS) to Increase Adherence With Digital Technology","A Randomized Controlled Trial in Lombok: Assessing Factors Influencing Acceptance and Adherence to Multiple Micronutrient Supplementation (MMS) Using Digital Tools","SMART-MMS","Inclusion Criteria:\n\n* Pregnant women up to 32 weeks\n* Pregnant women stay in the site at least during the study period\n\nExclusion Criteria:\n\n* Lost to follow up\n* Moving to another area\n* Death\n* Abortus\n* Stillbirth",true,"FEMALE","14 Years",{"count":92,"type":93},10012,"ESTIMATED","INTERVENTIONAL",[96],"NA","The goal of this randomized clinical trial is to learn whether a digital health intervention can improve adherence to Multiple Micronutrient Supplementation (MMS) among pregnant women in Lombok Island. The study also aims to understand how individual characteristics, socio-economic factors, maternal health status, and antenatal care services influence adherence to MMS.\n\nThe main questions it aims to answer are:\n\n1. Does a digitally supported intervention increase adherence to MMS compared to standard care?\n2. Does the type of MMS packaging (bottle vs. blister) affect adherence?\n3. In the second stage, does adding calcium supplementation affect adherence to MMS?\n\nResearchers will compare four groups to see if digital support and packaging type improve MMS adherence:\n\n1. Standard care with MMS in bottles\n2. Standard care with MMS in blister packs\n3. Digital intervention with MMS in bottles\n4. Digital intervention with MMS in blister packs\n\nApproximately 10,012 pregnant women will be randomly assigned to one of these four groups using a 2×2 factorial design.\n\nParticipants will:\n\n1. Receive MMS through either bottle or blister packaging\n2. Receive either standard care or a digital health intervention (such as reminders or digital support tools)\n3. Attend routine antenatal care services\n4. Be followed throughout pregnancy, delivery, and up to 42 days after childbirth\n\nIn the second stage of the study, participants from community health posts (Posyandu) will also receive calcium supplementation in addition to MMS. Additional 900 pregnant women will be enrolled from the same Puskesmas areas participating in the MMS study to evaluate the addition of calcium supplementation. These participants will be recruited outside of the main MMS cohort and will be equally distributed across the four study arms. This stage aims to assess whether adding calcium supplementation influences adherence to MMS among pregnant women.\n\nParticipants will be monitored during pregnancy, at delivery, and during the postnatal care period up to 42 days after birth.\n\nThis study represents an early implementation of Multiple Micronutrient Supplementation (MMS) in Lombok Island, where MMS is not yet routinely available through government programs. Only selected primary healthcare centers (Puskesmas) that are randomized into the study will provide MMS to eligible participants. While the government has begun introducing MMS in other areas, it has not yet been implemented in Lombok.\n\nThe digital health intervention will only be provided to pregnant women who agree to participate in the study and provide informed consent. All participants will continue to receive standard antenatal care (ANC) services in accordance with existing government programs.\n\nThis study is also integrated with the ongoing distribution of iron and folic acid supplementation (TTD) in Lombok. Pregnant women who do not consent to participate in the study or do not receive MMS will continue to receive TTD as part of routine care outside of the study.",[99,100],"Pregnancy","Adherence",[102,99,103,104,105],"MMS","Digitalization","adherence","Antenatal Care","2026-06-30",{"date":108,"type":109},"2026-07-01","ACTUAL",{"date":111,"type":109},"2026-06-13",{"date":113,"type":93},"2027-06",{"name":5,"class":6},1]