[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100606665":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":24,"centralContacts":28,"locations":34,"responsibleParty":51,"collaborators":54,"id":58,"slug":10,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":10,"eligibilityCriteria":63,"healthyVolunteers":64,"sex":65,"minAge":66,"maxAge":10,"enrollmentInfo":67,"targetDuration":10,"studyType":70,"phases":10,"briefSummary":71,"conditions":72,"keywords":10,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Mayo Clinic","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Spontaneous coronary artery dissection (SCAD)",null,"Subject has a history of spontaneous coronary artery dissection (SCAD)",[13],"Procedure: Stress Echocardiography with Contrast",{"label":15,"type":10,"description":16,"interventionNames":17},"Healthy Subjects","Subjects are healthy with no significant medical history",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"PROCEDURE","Stress Echocardiography with Contrast","Stress Echocardiography with Contrast will be used to assess heart function and blood flow response to stressors.",[15,9],[25],{"name":26,"affiliation":5,"role":27},"Marysia Tweet, M.D., M.S.","PRINCIPAL_INVESTIGATOR",[29],{"name":30,"role":31,"phone":32,"phoneExt":10,"email":33},"Pamela Engrav","CONTACT","507-255-6938","engrav.pamela@mayo.edu",[35],{"facility":5,"status":36,"city":37,"state":38,"zip":39,"country":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"RECRUITING","Rochester","Minnesota","55905","United States",{"type":42,"coordinates":43},"Point",[44,45],-92.4699,44.02163,{"lat":45,"lon":44},[48,49],{"name":30,"role":31,"phone":32,"phoneExt":10,"email":33},{"name":50,"role":27,"phone":10,"phoneExt":10,"email":10},"Marysia S Tweet, M.D., M.S.",{"type":27,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Marysia Tweet","Principal Investigator",[55],{"name":56,"class":57},"National Heart, Lung, and Blood Institute (NHLBI)","NIH","100606665",false,"NCT07178509","A Study of SCAD Using Stress Contrast Echocardiography","Myocardial Perfusion in Spontaneous Coronary Artery Dissection Using Stress Contrast Echocardiography","Inclusion Criteria:\n\n* Adult \\>18 years old\n* Patient has a history of spontaneous coronary artery dissection (SCAD) OR patient is healthy with no significant medical history\n\nExclusion Criteria:\n\n* Unable to give consent\n* Allergic or have a history of adverse reaction to dobutamine, the Definity® ultrasound enhancing agent, or atropine.\n* Has a known or suspected hypersensitivity to perflutren and therefore cannot be given Definity®.\n* Pregnant.\n* Unable to interrupt breastfeeding.\n* Within 3 months of a heart attack.\n* Severe aortic stenosis.\n* Severe, uncontrolled hypertension (\\>200\u002F110 mmHg at baseline).",true,"ALL","18 Years",{"count":68,"type":69},50,"ESTIMATED","OBSERVATIONAL","This study aims to fill knowledge gaps regarding microvascular perfusion and pressor response to stress among patients with history of spontaneous coronary artery dissection (SCAD) using stress contrast echocardiography.",[73],"Spontaneous Coronary Artery Dissection","2026-01-06",{"date":76,"type":77},"2026-01-07","ACTUAL",{"date":79,"type":77},"2025-11-25",{"date":81,"type":69},"2027-09",{"name":5,"class":6},1]