A Study of the Use of Fat Flap Reconstruction to Reduce Neck Injury After Cancer Treatment

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorMemorial Sloan Kettering Cancer Center

About this trial

The purpose of this study is to find out whether the fat ALT flap procedure is a safe and practical option for reducing neck morbidity in HNSCC patients following cancer treatment of the neck. Neck morbidity after radiation therapy and surgery includes difficulty swallowing, neck or shoulder pain, stiffness, swelling, or changes to the appearance of the treated area. In addition, the researchers will find out whether the study procedure is effective at reducing neck morbidity and improving quality of life after cancer treatment. The researchers will measure quality of life by having participants answer questionnaires.

Eligibility criteria

Qualifiers

Patients 18 years or older

Diagnosed with HNSCC (e.g., oropharyngeal, hypo/laryngeal SCC)

Primary treatment is with radiotherapy with or without chemotherapy

Salvage neck dissection is subsequently indicated for persistent or recurrent, nonmucosal disease in cervical lymph nodes

Disqualifiers

Patients with primary site mucosal recurrence in addition to neck disease

Trial design

Treatments tested in this trial

  • HRQOL instruments
  • LENT SOMA instrument

Treatment groups

12 Participants
are divided into 1 treatment group

Locations

1
Memorial Sloan Kettering Cancer Center (All Protocol Activities)10065, New YorkNew York, United States

Sponsors and collaborators

Memorial Sloan Kettering Cancer Center

Lead sponsor