[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100530954":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":38,"responsibleParty":56,"collaborators":25,"id":60,"slug":25,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":63,"acronym":25,"eligibilityCriteria":64,"healthyVolunteers":61,"sex":65,"minAge":25,"maxAge":25,"enrollmentInfo":66,"targetDuration":25,"studyType":69,"phases":70,"briefSummary":72,"conditions":73,"keywords":75,"overallStatus":41,"whyStopped":25,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":89},{"fullName":5,"class":6},"Karolinska Institutet","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Platelet rich plasma (PRP)","ACTIVE_COMPARATOR","High-concentration PRP injection PRP injection (0,6-1ml). Arthrex ACPmax system.",[13],"Procedure: Platelet rich plasma (PRP)",{"label":15,"type":16,"description":17,"interventionNames":18},"Placebo","PLACEBO_COMPARATOR","intraarticular saline injection (0,6-1ml)",[19],"Other: Placebo",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Intra-articular injection of platelet rich plasma (PRP)",[9],null,{"type":6,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Intra-articular Saline injection (0,6-1ml)",[15],[30,35],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Maria Wilcke, MD, PhD","CONTACT","+46708294613","maria.wilcke@regionstockholm.se",{"name":36,"role":32,"phone":25,"phoneExt":25,"email":37},"Johanna VonKieseritzky, MD. PhD","johanna.vonkieseritzky@regionstockholm.se",[39],{"facility":40,"status":41,"city":42,"state":25,"zip":43,"country":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Department of Hand Surgery Södersjukhuset","RECRUITING","Stockholm","S-11883","Sweden",{"type":46,"coordinates":47},"Point",[48,49],18.06871,59.32938,{"lat":49,"lon":48},[52,54],{"name":53,"role":32,"phone":33,"phoneExt":25,"email":34},"Maria Wilcke, PhD",{"name":55,"role":32,"phone":25,"phoneExt":25,"email":37},"Johanna Von Kieseritzky, PhD",{"type":57,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Maria Wilcke","Associate profesoor","100530954",false,"NCT06193499","A Study on the Effect of High-concentrated Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base.","Inclusion Criteria:\n\n* Osteoarthritis in the thumb base\n* Radiological Eaton Littler class 1-3.\n* Clinical signs of thumb base osteoarthritis )pain at palpation of the CMC-1 joint and pain during provocation\u002Fgrinding test).\n\nExclusion Criteria:\n\n* Rheumatoid arthritis\n* Ongoing infection in the hand or wrist\n* History of gout or pseudogout in the hand\n* Inability to co-operate with the follow-up protocol (language difficulties, severe psychiatric disorder, cognitive impairment, drug addiction).\n* Chronic pain syndrome \u002F centralized pain.\n* Intra-articular injection in the affected joint within 6 months.\n* Eaton Littler class 4 (symptomatic STT joint osteoarthritis).","ALL",{"count":67,"type":68},90,"ESTIMATED","INTERVENTIONAL",[71],"NA","This is a randomized double-blinded randomized comparison between injection of platelet rich plasma (PRP) and placebo for thumb basale osteoarthritis.",[74],"Osteoarthritis Thumb",[76,77,78,79],"CMC-1 joint","thumb basal joint","PRP","Platelet-rich plasma","2025-06-01",{"date":82,"type":83},"2025-06-03","ACTUAL",{"date":85,"type":83},"2024-01-17",{"date":87,"type":68},"2027-06-30",{"name":5,"class":6},1]