[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100266135":3},{"organization":4,"armGroups":7,"interventions":27,"overallOfficials":38,"centralContacts":43,"locations":52,"responsibleParty":69,"collaborators":73,"id":80,"slug":33,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":33,"eligibilityCriteria":85,"healthyVolunteers":81,"sex":86,"minAge":87,"maxAge":88,"enrollmentInfo":89,"targetDuration":33,"studyType":92,"phases":93,"briefSummary":95,"conditions":96,"keywords":98,"overallStatus":55,"whyStopped":33,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":111},{"fullName":5,"class":6},"Sun Yat-sen University","OTHER",[8,14,19,23],{"label":9,"type":10,"description":11,"interventionNames":12},"High-level tumor budding group with CLND","EXPERIMENTAL","Resection for primary lesion and cervical lymph node dissection (CLND) are performed in the early-stage oral squamous cell carcinoma which tumor budding is a high level.",[13],"Procedure: Resection for primary lesion and cervical lymph node dissection",{"label":15,"type":10,"description":16,"interventionNames":17},"High-level tumor budding group without CLND","Only resection for primary lesion is performed in the early-stage oral squamous cell carcinoma which tumor budding is a high level.",[18],"Procedure: Resection for primary lesion only",{"label":20,"type":10,"description":21,"interventionNames":22},"Low-level tumor budding group with CLND","Resection for primary lesion and cervical lymph node dissection (CLND) are performed in the early-stage oral squamous cell carcinoma which tumor budding is a low level.",[13],{"label":24,"type":10,"description":25,"interventionNames":26},"Low-level tumor budding group without CLND","Only resection for primary lesion is performed in the early-stage oral squamous cell carcinoma which tumor budding is a low level.",[18],[28,34],{"type":29,"name":30,"description":31,"armGroupLabels":32,"otherNames":33},"PROCEDURE","Resection for primary lesion and cervical lymph node dissection","Resection for primary lesion and cervical lymph node dissection are performed in the early-stage oral squamous cell carcinoma.",[9,20],null,{"type":29,"name":35,"description":36,"armGroupLabels":37,"otherNames":33},"Resection for primary lesion only","Only resection for primary lesion is performed in the early-stage oral squamous cell carcinoma.",[15,24],[39],{"name":40,"affiliation":41,"role":42},"Jinsong Hou, PhD","Guanghua School of Stomatology, Hospital of Stomatolagy Sun Yat-sen University","STUDY_DIRECTOR",[44,48],{"name":40,"role":45,"phone":46,"phoneExt":33,"email":47},"CONTACT","86-13825141651","houjsgz@aliyun.com",{"name":49,"role":45,"phone":50,"phoneExt":33,"email":51},"Cheng Wang, PhD","86-13760853366","drwangcheng@outlook.com",[53],{"facility":54,"status":55,"city":56,"state":57,"zip":58,"country":59,"cosmosGeoPoint":60,"geoPoint":65,"contacts":66},"Guanghua School of Stomatolagy, Hospital of Stomatology Sun Yat-sen University","RECRUITING","Guangzhou","Guangdong","510055","China",{"type":61,"coordinates":62},"Point",[63,64],113.25,23.11667,{"lat":64,"lon":63},[67,68],{"name":40,"role":45,"phone":46,"phoneExt":33,"email":47},{"name":49,"role":45,"phone":50,"phoneExt":33,"email":51},{"type":70,"investigatorFullName":71,"investigatorTitle":72,"investigatorAffiliation":5,"oldNameTitle":33,"oldOrganization":33},"SPONSOR_INVESTIGATOR","Jinsong Hou","Vice Director",[74,76,78],{"name":75,"class":6},"First Affiliated Hospital, Sun Yat-Sen University",{"name":77,"class":6},"Second Affiliated Hospital, Sun Yat-Sen University",{"name":79,"class":6},"Hospital of Stomatology, Sun Yat-Sen University","100266135",false,"NCT02743832","A Study on Tumor Budding Guiding Individualized Surgical Planning of Early-stage Oral Squamous Cell Carcinoma.","A Randomized，Multicenter，Prospectie，Controlled Clinical Study on Tumor Budding Guiding Individualized Surgical Planning of Early-stage Oral Squamous Cell Carcinoma.","Inclusion Criteria:\n\n1. Han race;\n2. Oral squamous cell carcinoma is confirmed by pathology;\n3. The section of oral squamous cell carcinoma including primary two-thirds prior to the tongue, buccal mucosa， gingiva， mouth floor， hard palate mucosa;\n4. The primary lesion is no more than 4cm;\n5. Do not find cervical lymph node metastases and distant metastasis in the clinical examination including physical examination and MRI;\n6. Patients and families agree to participate in the study;\n7. Patients do not have cognitive disorders.\n\nExclusion Criteria:\n\n1. Do not meet the inclusion criteria;\n2. The primary lesion is more than 4cm or invade adjacent tissues;\n3. Do not review on schedule;\n4. Patients receive not only surgical procedures, but other antineoplastic treatment;\n5. There are serious adverse events after operation;\n6. Patients quit the study voluntarily;\n7. Patients quit the study because of physical condition.","ALL","20 Years","70 Years",{"count":90,"type":91},524,"ESTIMATED","INTERVENTIONAL",[94],"NA","The purpose of this study is to determine whether cervical lymph node dissection is necessarily performed in the presence of early-stage oral squamous cell carcinoma.",[97],"Carcinoma, Squamous Cell",[99,100,101],"Oral squamous cell carcinoma","Tumor budding","Cervical lymph node dissection","2026-04-24",{"date":104,"type":105},"2026-04-30","ACTUAL",{"date":107,"type":91},"2026-05-04",{"date":109,"type":91},"2027-06-30",{"name":71,"class":6},1]