[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100567398":3},{"organization":4,"armGroups":7,"interventions":25,"overallOfficials":24,"centralContacts":34,"locations":40,"responsibleParty":68,"collaborators":24,"id":70,"slug":24,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":24,"eligibilityCriteria":75,"healthyVolunteers":71,"sex":76,"minAge":77,"maxAge":24,"enrollmentInfo":78,"targetDuration":24,"studyType":81,"phases":82,"briefSummary":84,"conditions":85,"keywords":24,"overallStatus":43,"whyStopped":24,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Uppsala University","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention group","EXPERIMENTAL","Participants will receive cognitive behavioral therapy treatment (iCBT) for prolonged grief.",[13],"Behavioral: iCBT for prolonged grief",{"label":15,"type":16,"description":17,"interventionNames":18},"Active control","ACTIVE_COMPARATOR","Participants will receive psychoeducation about grief and common grief reactions.",[19],"Behavioral: Active control",{"label":21,"type":22,"description":23,"interventionNames":24},"Waitlist control","NO_INTERVENTION","Participants will be offered the iCBT treatment for prolonged grief after 10 weeks.",null,[26,31],{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":24},"BEHAVIORAL","iCBT for prolonged grief","Participants will undergo a 10-week internet-delivered, therapist-led cognitive behavioral therapy treatment (iCBT) for prolonged grief, which includes psychoeducation about grief and common grief reactions, exposure, cognitive restructuring and behavioral activation.",[9],{"type":27,"name":15,"description":32,"armGroupLabels":33,"otherNames":24},"Participants will undergo a 10-week internet-delivered, therapist-led treatment, which includes psychoeducation about grief and common grief reactions.",[15],[35],{"name":36,"role":37,"phone":38,"phoneExt":24,"email":39},"Josefin Sveen, Professor","CONTACT","+46 738 66 70 87","josefin.sveen@uu.se",[41,58],{"facility":42,"status":43,"city":44,"state":24,"zip":45,"country":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"Region Uppsala, KBT via nätet, Nära vård digitalt","RECRUITING","Uppsala","751 85","Sweden",{"type":48,"coordinates":49},"Point",[50,51],17.63889,59.85882,{"lat":51,"lon":50},[54],{"name":55,"role":37,"phone":56,"phoneExt":24,"email":57},"Lina Ciardella, Lic. psychologist","+46186172167","lina.ciardella@regionuppsala.se",{"facility":59,"status":43,"city":44,"state":24,"zip":60,"country":46,"cosmosGeoPoint":61,"geoPoint":63,"contacts":64},"Uppsala university, Dep of Womens and Childrens Health","75185",{"type":48,"coordinates":62},[50,51],{"lat":51,"lon":50},[65],{"name":66,"role":37,"phone":67,"phoneExt":24,"email":39},"Josefin Sveen, Phd","+46184715478",{"type":69,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR","100567398",false,"NCT06667674","A Swedish Internet CBT for Prolonged Grief Disorder: a Three-armed RCT","Efficacy and Mechanisms of Change of Online Cognitive Behavioural Therapy for Prolonged Grief Disorder After Loss: a Three-armed Randomised Control Trial","Inclusion Criteria:\n\n* Currently residing in Sweden\n* Lost a relative or close friend to any cause of death at least six months ago\n* Suffers from prolonged grief disorder\n\nExclusion Criteria:\n\n* Ongoing severe psychiatric problems that may prevent treatment implementation or require more urgent care (e.g., participants with untreated psychotic disorder, untreated bipolar disorder, ongoing substance abuse, elevated suicide risk)\n* Change in dosage of any medication for mental health issues (e.g., antidepressant medication) in the past four weeks or in the next two months","ALL","18 Years",{"count":79,"type":80},270,"ESTIMATED","INTERVENTIONAL",[83],"NA","The goal of this clinical trial is to evaluate the effectiveness of internet-delivered Cognitive Behavioral Therapy (iCBT) in reducing symptoms of prolonged grief in adults diagnosed with prolonged grief disorder.\n\nThe main questions the study aims to answer are:\n\n* Does iCBT reduce symptoms of prolonged grief disorder, posttraumatic stress, and depression following the death of a loved one in the short and long term?\n* What mechanisms contribute to the effectiveness of iCBT in treating prolonged grief disorder?\n\nThe iCBT intervention will be compared to a waitlist control group and an active control group to see if iCBT reduces symptoms of prolonged grief disorder more effectively than no treatment or a placebo treatment.\n\nParticipants will:\n\n* Be randomly assigned to either the iCBT group, an active control group or a waitlist control group\n* Complete online assessments of symptom severity, grief cognitions, and level of avoidance before, during and after intervention\n* Engage in 10 weeks of a therapist-guided online treatment",[86],"Prolonged Grief Disorder","2025-04-24",{"date":89,"type":90},"2025-04-29","ACTUAL",{"date":92,"type":90},"2025-04-23",{"date":94,"type":80},"2028-07",{"name":5,"class":6},2]