Acute Treatment and Long-term Assessment of Adult Infectious Meningitis
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorHospital Israelita Albert Einstein
About this trial
Prospective, multicenter, observational clinical registry of adult patients with acute infectious meningitis across approximately 30 public and private hospitals in Brazil. The study will include adults, 18 years old and older, with suspected acute infectious meningitis. Data will be collected during hospitalization and post-discharge to evaluate clinical management, treatment and short and long-term outcomes. The study aims to generate real-world evidence on current practices and outcomes to support improvements in national care protocols.
Eligibility criteria
Qualifiers
Fever (axillary temperature ≥37.8°C) followed by two or more of the following symptoms: severe headache, vomiting, altered consciousness (confusion, drowsiness, or irritability), photophobia (increased sensitivity to light), presence of seizures OR
Fever accompanied by at least one meningeal irritation sign, such as neck stiffness, Kernig's sign, or Brudzinski's sign OR
Sudden onset of fever and appearance of petechial skin rash or hemorrhagic suffusions
Disqualifiers
None
Trial design
Treatments tested in this trial
- Not listed
Trial groups
No trial groups listed
Locations
3Hospital São Vicente de Paulo99010-080, Passo FundoRio Grande do Sul, Brazil
Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto - USP14051-140, Ribeirão PretoSão Paulo, Brazil
Hospital Santa Marcelina08270-070, São PauloSão Paulo, Brazil
Sponsors and collaborators
Hospital Israelita Albert Einstein
Lead sponsor
Ministry of Health, Brazil
Collaborator
Source ClinicalTrials.gov