About this trial
This clinical trial evaluates if in-person acupuncture or virtual acupressure therapy prevents aromatase inhibitor-associated joint pain in Non-Hispanic Black postmenopausal women with stage I-III (early-stage) hormone receptor positive (HR+) breast cancer. Aromatase inhibitors (AI) are medications that prevent the formation of the hormone estrogen. They are used in the treatment of postmenopausal women who have hormone-dependent breast cancer. AI therapy prolongs life among patients with early-stage HR+ breast cancer. Many postmenopausal women stop AI therapy early due to debilitating joint pain (arthralgias). Non-Hispanic Black women are more likely to experience side effects and stop their hormonal therapy compared to Non-Hispanic white women. Acupuncture therapy involves inserting thin needles through the skin at specific points on the body to control pain. Acupressure therapy uses the application of pressure or localized massage to specific sites on the body to control symptoms such as pain. Acupuncture and acupressure are types of complementary and alternative medicine. Undergoing in-person acupuncture or participating in virtual acupressure may prevent AI-associated arthralgias (AIAA) in Non-Hispanic Black postmenopausal women with early-stage HR+ breast cancer.
Eligibility criteria
Qualifiers
Age ≥ 18 years
Self-identified Non-Hispanic Black woman
Postmenopausal status (>= 12 months since last menstrual period, history of bilateral salpingo-oophorectomy, or estradiol, follicle-stimulating hormone [FSH], and luteinizing hormone [LH] levels consistent with menopause)
Diagnosed with stage I-III HR+/HER2 negative (-) breast cancer
Disqualifiers
Diagnosed with metastatic breast cancer
Premenopausal status
History of allergic reactions attributed to compounds of similar chemical or biologic composition to acupuncture needles or other agents used in study
Diagnosis of rheumatoid arthritis, multiple sclerosis, or muscular dystrophy
Trial design
Treatments tested in this trial
- Acupressure Therapy
- Acupuncture Therapy
- Aromatase Inhibition Therapy
- Discussion
- Survey Administration
Treatment groups
Locations
4Sponsors and collaborators
Emory University
Lead sponsor
Bristol-Myers Squibb
Collaborator
National Cancer Institute (NCI)
Collaborator