[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100625679":3},{"organization":4,"armGroups":7,"interventions":15,"overallOfficials":21,"centralContacts":26,"locations":35,"responsibleParty":54,"collaborators":56,"id":60,"slug":21,"hasResults":61,"nctId":62,"briefTitle":63,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":61,"sex":67,"minAge":21,"maxAge":21,"enrollmentInfo":68,"targetDuration":21,"studyType":71,"phases":72,"briefSummary":74,"conditions":75,"keywords":21,"overallStatus":37,"whyStopped":21,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"University of Kansas Medical Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Remote Exercise and Caregiver Education","EXPERIMENTAL","Single Arm with active intervention for remote exercise and caregiver education sessions",[13,14],"Behavioral: Remote Exercise Sessions","Behavioral: Caregiver Education Sessions",[16,22],{"type":17,"name":18,"description":19,"armGroupLabels":20,"otherNames":21},"BEHAVIORAL","Remote Exercise Sessions","Participants will take part in thrice weekly exercise sessions using pre-recorded videos designed for older adults with Down syndrome. Participants will join video call and follow along with the video. A staff member familiar with the population will be on the call to provide modifications, encouragement and ensure participant safety.",[9],null,{"type":17,"name":23,"description":24,"armGroupLabels":25,"otherNames":21},"Caregiver Education Sessions","Caregivers will join a once-weekly education session held via video call and led by a trained staff member. Education content will include how to support and manage challenging behaviors of older adults with Down syndrome who may be experiencing Alzheimer's disease-related symptoms.",[9],[27,32],{"name":28,"role":29,"phone":30,"phoneExt":21,"email":31},"Amy Bodde, PhD","CONTACT","913-574-2447","abodde@kumc.edu",{"name":33,"role":29,"phone":21,"phoneExt":21,"email":34},"Joseph Sherman, MS","jsherman7@kumc.edu",[36],{"facility":5,"status":37,"city":38,"state":39,"zip":40,"country":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"RECRUITING","Kansas City","Kansas","66160","United States",{"type":43,"coordinates":44},"Point",[45,46],-94.62746,39.11417,{"lat":46,"lon":45},[49,50,52],{"name":28,"role":29,"phone":30,"phoneExt":21,"email":31},{"name":51,"role":29,"phone":21,"phoneExt":21,"email":34},"Joseph Sherman",{"name":28,"role":53,"phone":21,"phoneExt":21,"email":21},"PRINCIPAL_INVESTIGATOR",{"type":55,"investigatorFullName":21,"investigatorTitle":21,"investigatorAffiliation":21,"oldNameTitle":21,"oldOrganization":21},"SPONSOR",[57],{"name":58,"class":59},"National Center for Advancing Translational Sciences (NCATS)","NIH","100625679",false,"NCT07425769","Adapting RDAD for DS","Adapting the RDAD Intervention for Individuals With Down Syndrome Phase 3- Pilot Test","CareFit DS\u002FAD","Inclusion Criteria - Adults with Down syndrome:\n\n* Age \\>35 yrs. with a diagnosis of DS as self-reported or reported by caregiver. This age range was selected as cognitive decline related to AD is observed at age \\~31 in adults with DS.\n* Sufficient functional ability to understand directions, communicate preferences, wants, and needs through spoken language.\n* Living at home or in a supported living environment with a parent\u002Fcaregiver who agrees to serve as a study partner.\n* Self-reported ability to participate in physical activity.\n\nExclusion Criteria - Adults with Down syndrome:\n\n* Unable to participate in moderate-to-vigorous physical activity.\n* Self-reported, cardiovascular, metabolic or renal disease and\u002For signs or symptoms.\n\nInclusion Criteria - Caregivers\n\n* Age ≥18 yrs.\n* Reports being a primary caregiver of an adult with DS.\n* English speaking.\n* Self-reported ability to participate in physical activity.\n\nExclusion Criteria - Caregivers\n\n* Unable to participate in moderate PA, i.e., brisk walking.\n* Self-reported, cardiovascular, metabolic or renal disease and\u002For signs or symptoms.","ALL",{"count":69,"type":70},40,"ESTIMATED","INTERVENTIONAL",[73],"NA","The goal of this clinical trial is to observe feasibility and initial efficacy of a remotely delivered exercise and dementia caregiving intervention in older adults with Down syndrome and their caregivers.",[76,77],"Down Syndrome (DS)","Alzheimer's Disease (AD)","2026-05-05",{"date":80,"type":81},"2026-05-06","ACTUAL",{"date":83,"type":81},"2026-03-31",{"date":85,"type":70},"2026-07-31",{"name":5,"class":6},1]