Adaptive Randomization of Aerobic Exercise During Chemotherapy in Colon Cancer

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorAdventHealth Translational Research Institute

About this trial

To goal of this clinical trial is to quantify the dose-response effects of aerobic exercise training compared to attention control on chemotherapy relative dose intensity in colon cancer survivors.

Eligibility criteria

Qualifiers

Age ≥18 years

Histologically confirmed stage II or III colon cancer

Completed surgical resection with curative intent

Plan to initiate chemotherapy

Disqualifiers

Evidence of metastatic colon cancer

Concurrently actively treated other (non-colon) cancer

Currently pregnant, breastfeeding, or planning to become pregnant within the next 24 weeks

Currently participating in another study with competing outcomes

Trial design

Treatments tested in this trial

  • Aerobic exercise
  • Progressive stretching

Treatment groups

219 Participants
are divided into 5 treatment groups

Locations

3
Kaiser Permanente Northern California94612, OaklandCalifornia, United States
AdventHealth32804, OrlandoFlorida, United States
Dana-Farber Cancer Institute02215, BostonMassachusetts, United States

Sponsors and collaborators

AdventHealth Translational Research Institute

Lead sponsor

National Cancer Institute (NCI)

Collaborator