[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100587722":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":24,"locations":33,"responsibleParty":175,"collaborators":10,"id":178,"slug":10,"hasResults":179,"nctId":180,"briefTitle":181,"officialTitle":182,"acronym":183,"eligibilityCriteria":184,"healthyVolunteers":179,"sex":185,"minAge":186,"maxAge":10,"enrollmentInfo":187,"targetDuration":190,"studyType":191,"phases":10,"briefSummary":192,"conditions":193,"keywords":202,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":219,"lastUpdatePostDateStruct":220,"startDateStruct":223,"completionDateStruct":225,"leadSponsor":227,"locationsCount":228},{"fullName":5,"class":6},"Leiden University Medical Center","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"ACHD patients treated with SGLT2i",null,"All participants included in the registry have to have a congenital heart defect, be ≥ 18 years old, and receive (or have received) treatment with SGLT2i.",[13],"Drug: SGLT2 inhibitors",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DRUG","SGLT2 inhibitors","Treatment with any type and dose of sodium-glucose cotransporter 2 inhibitor.",[9],[21],{"name":22,"affiliation":5,"role":23},"Anastasia D. Egorova, MD PhD","PRINCIPAL_INVESTIGATOR",[25,30],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"Ralph M.L. Neijenhuis, MD","CONTACT","+31 71 5262020","r.m.l.neijenhuis@lumc.nl",{"name":31,"role":27,"phone":28,"phoneExt":10,"email":32},"Björn N. Westdorp, MD","b.n.westdorp@lumc.nl",[34,50,63,75,90,107,118,129,141,153,164],{"facility":35,"status":36,"city":37,"state":38,"zip":39,"country":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Johns Hopkins University","RECRUITING","Baltimore","Maryland","21205","United States",{"type":42,"coordinates":43},"Point",[44,45],-76.61219,39.29038,{"lat":45,"lon":44},[48],{"name":49,"role":23,"phone":10,"phoneExt":10,"email":10},"Ari M. Cedars, MD PhD",{"facility":51,"status":36,"city":52,"state":53,"zip":54,"country":40,"cosmosGeoPoint":55,"geoPoint":59,"contacts":60},"Helen DeVos Children's Hospital","Grand Rapids","Michigan","49503",{"type":42,"coordinates":56},[57,58],-85.66809,42.96336,{"lat":58,"lon":57},[61],{"name":62,"role":23,"phone":10,"phoneExt":10,"email":10},"Gruschen R. Veldtman, MBChB FRCP",{"facility":64,"status":36,"city":65,"state":65,"zip":66,"country":40,"cosmosGeoPoint":67,"geoPoint":71,"contacts":72},"Mount Sinai Fuster Heart Hospital","New York","10029",{"type":42,"coordinates":68},[69,70],-74.00597,40.71427,{"lat":70,"lon":69},[73],{"name":74,"role":23,"phone":10,"phoneExt":10,"email":10},"Ali Zaidi, MD",{"facility":76,"status":36,"city":77,"state":10,"zip":10,"country":78,"cosmosGeoPoint":79,"geoPoint":83,"contacts":84},"Heart Center Duisburg (Evangelical Hospital Niederrhein)","Duisburg","Germany",{"type":42,"coordinates":80},[81,82],6.76516,51.43247,{"lat":82,"lon":81},[85,87],{"name":86,"role":23,"phone":10,"phoneExt":10,"email":10},"Paul Hacke, MD",{"name":88,"role":89,"phone":10,"phoneExt":10,"email":10},"Anas Shihab, MD","SUB_INVESTIGATOR",{"facility":91,"status":36,"city":92,"state":93,"zip":94,"country":95,"cosmosGeoPoint":96,"geoPoint":100,"contacts":101},"Leiden University Medical Center (LUMC)","Leiden","South Holland","2333ZA","Netherlands",{"type":42,"coordinates":97},[98,99],4.49306,52.15833,{"lat":99,"lon":98},[102,103,104,105,106],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},{"name":31,"role":27,"phone":28,"phoneExt":10,"email":32},{"name":22,"role":23,"phone":10,"phoneExt":10,"email":10},{"name":26,"role":89,"phone":10,"phoneExt":10,"email":10},{"name":31,"role":89,"phone":10,"phoneExt":10,"email":10},{"facility":108,"status":36,"city":109,"state":10,"zip":10,"country":95,"cosmosGeoPoint":110,"geoPoint":114,"contacts":115},"Amsterdam University Medical Center","Amsterdam",{"type":42,"coordinates":111},[112,113],4.88969,52.37403,{"lat":113,"lon":112},[116],{"name":117,"role":23,"phone":10,"phoneExt":10,"email":10},"Berto J. Bouma, MD PhD",{"facility":119,"status":36,"city":120,"state":10,"zip":10,"country":95,"cosmosGeoPoint":121,"geoPoint":125,"contacts":126},"University Medical Center Utrecht","Utrecht",{"type":42,"coordinates":122},[123,124],5.12222,52.09083,{"lat":124,"lon":123},[127],{"name":128,"role":23,"phone":10,"phoneExt":10,"email":10},"Heleen B. Van Der Zwaan, MD PhD",{"facility":130,"status":36,"city":131,"state":10,"zip":10,"country":132,"cosmosGeoPoint":133,"geoPoint":137,"contacts":138},"Zan Mitrev Clinic","Skopje","North Macedonia",{"type":42,"coordinates":134},[135,136],21.43141,41.99646,{"lat":136,"lon":135},[139],{"name":140,"role":23,"phone":10,"phoneExt":10,"email":10},"Milka Klinceva, MD PhD",{"facility":142,"status":36,"city":143,"state":10,"zip":10,"country":144,"cosmosGeoPoint":145,"geoPoint":149,"contacts":150},"University Hospital of Wales","Cardiff","United Kingdom",{"type":42,"coordinates":146},[147,148],-3.18,51.48,{"lat":148,"lon":147},[151],{"name":152,"role":23,"phone":10,"phoneExt":10,"email":10},"Simon T. MacDonald, MD DPhil",{"facility":154,"status":36,"city":155,"state":10,"zip":10,"country":144,"cosmosGeoPoint":156,"geoPoint":160,"contacts":161},"Golden Jubilee University National Hospital","Glasgow",{"type":42,"coordinates":157},[158,159],-4.25763,55.86515,{"lat":159,"lon":158},[162],{"name":163,"role":23,"phone":10,"phoneExt":10,"email":10},"Niki L. Walker, MBChB PhD",{"facility":165,"status":36,"city":166,"state":10,"zip":10,"country":144,"cosmosGeoPoint":167,"geoPoint":171,"contacts":172},"Barts Heart Centre","London",{"type":42,"coordinates":168},[169,170],-0.12574,51.50853,{"lat":170,"lon":169},[173],{"name":174,"role":23,"phone":10,"phoneExt":10,"email":10},"Filip Zemrak, MD PhD",{"type":23,"investigatorFullName":176,"investigatorTitle":177,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Anastasia D. Egorova, MD, PhD","Principal Investigator","100587722",false,"NCT06932081","Adult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i Registry","Adult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i (ACHIEVE-SGLT2i) Registry","ACHIEVE-SGLT2i","Inclusion Criteria:\n\n* Congenital heart defect.\n* Age ≥ 18 years.\n* Initiated on treatment with an SGLT2i.\n\nExclusion Criteria:\n\n\\- No consent for data collection.","ALL","18 Years",{"count":188,"type":189},400,"ESTIMATED","1 Year","OBSERVATIONAL","This real-world, international registry aims to evaluate the current experience with sodium-glucose cotransporter 2 inhibitors (SGLT2i) in adult congenital heart disease (ACHD) patients by investigating the prescription patterns, safety, tolerability, and potential beneficial effects on heart failure-related outcomes.",[194,195,196,197,198,199,200,201],"Adult Congenital Heart Disease","Congenital Heart Disease","Systemic Right Ventricle","Transposition of the Great Arteries","Congenitally Corrected Transposition of the Great Arteries","Fontan","Single Ventricle","Tetralogy of Fallot (TOF)",[203,204,205,206,207,208,209,210,211,212,213,214,215,199,216,217,218],"adult congenital heart disease","ACHD","congenital heart disease","CHD","sodium-glucose cotransporter 2 inhibitors","SGLT2i","SGLT2","heart failure","HF","transposition of the great arteries","TGA","systemic right ventricle","sRV","single ventricle","tetralogy of fallot","ToF","2026-02-11",{"date":221,"type":222},"2026-02-13","ACTUAL",{"date":224,"type":222},"2023-01-01",{"date":226,"type":189},"2027-12-31",{"name":5,"class":6},11]