About this trial

This study evaluates how advanced endoscopic resection techniques affect treatment outcomes in adults with rectal cancer.

Rectal cancer has traditionally been treated with standard abdominal surgery. Newer endoscopic techniques allow removal of selected early tumors and may reduce treatment-related complications. However, their effectiveness and safety in tumors with deeper invasion are not yet fully established.

This multicenter retrospective observational study uses existing medical records from adults who underwent endoscopic or surgical resection of rectal tumors between 2015 and 2025. Researchers will analyze anonymized information on procedures performed and treatment outcomes to assess the safety and effectiveness of advanced endoscopic approaches.

The results of this study may help guide treatment selection and improve care for people with rectal cancer.

Eligibility criteria

Qualifiers

Patients with rectal neoplasms treated by advanced endoscopic resection

Disqualifiers

hybrid resection performed

full-thickness resection performed

essential procedural or outcome data were unavailable

Trial design

Treatments tested in this trial

  • Endoscopic submucosal dissection
  • Endoscopic intramuscular dissection

Treatment groups

300 Participants
are divided into 2 treatment groups

Locations

1
Jagiellonian University in Krakow31061, Krakow Poland

Sponsors and collaborators

Jagiellonian University

Lead sponsor