[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100600931":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":27,"locations":33,"responsibleParty":52,"collaborators":11,"id":54,"slug":11,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":11,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":11,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":72,"overallStatus":36,"whyStopped":11,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Yale University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Moderate-Intensity Exercise","EXPERIMENTAL",null,[13],"Behavioral: Moderate-Intensity Exercise",{"label":15,"type":6,"description":16,"interventionNames":17},"Low-Intensity Exercise","Control",[18],"Behavioral: Low-Intensity Exercise",[20,24],{"type":21,"name":9,"description":22,"armGroupLabels":23,"otherNames":11},"BEHAVIORAL","Participants will engage in 20 minutes of cycling at approximately 70% max heart rate with a 2.5 minute warm up and a 2.5 minute cool down.",[9],{"type":21,"name":15,"description":25,"armGroupLabels":26,"otherNames":11},"Participants will engage in 20 minutes of cycling at approximately 40-50% max heart rate with a 2.5 minute warm up and a 2.5 minute cool down.",[15],[28],{"name":29,"role":30,"phone":31,"phoneExt":11,"email":32},"Emily Weiss, PhD","CONTACT","203-858-1225","emily.weiss@yale.edu",[34],{"facility":35,"status":36,"city":37,"state":38,"zip":39,"country":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"Temple Medical Center","RECRUITING","New Haven","Connecticut","06511","United States",{"type":42,"coordinates":43},"Point",[44,45],-72.92816,41.30815,{"lat":45,"lon":44},[48,49],{"name":29,"role":30,"phone":11,"phoneExt":11,"email":32},{"name":50,"role":51,"phone":11,"phoneExt":11,"email":11},"Thomas Adams, PhD","PRINCIPAL_INVESTIGATOR",{"type":51,"investigatorFullName":50,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"Associate Professor","100600931",false,"NCT07103902","Aerobic Exercise and Obsessive-Compulsive Disorder Symptoms","Effects of Aerobic Exercise on Obsessive-Compulsive Disorder Symptoms and Cognitive Flexibility","Inclusion Criteria:\n\n* Adults, age 18 to 64 years\n* Meet diagnostic criteria for OCD (per the DIAMOND)\n* Stable psychiatric or medication treatment (if ≥4-weeks), or if no active treatment. Psychotropic medications will be reviewed with the study psychiatrist on a case by case basis.\n\nExclusion Criteria:\n\n* Active or unmanaged psychotic disorders, pervasive developmental disorders, bipolar disorder, current substance use disorder (moderate-to-severe), or high risk for suicide (defined as attempt, plan, or intent within past 3 months)\n* Documented motor impairments and medical condition(s) that prohibit physical exercise\n* Those who are pregnant or trying to become pregnant","ALL","18 Years","64 Years",{"count":64,"type":65},50,"ESTIMATED","INTERVENTIONAL",[68],"NA","The purpose of this study is to examine the acute effects of exercise on cognitive flexibility and symptom reactivity. The main questions it aims to answer are:\n\nDoes moderate intensity physical activity reduce subjective distress, compulsive urges, and intrusions- and increase cognitive flexibility- in adults with obsessive-compulsive disorder compared to low-intensity physical activity?\n\nResearchers will compare low- to moderate-intensity exercise to see if moderate physical activity increases cognitive flexibility and reduces symptom reactivity in adults with obsessive-compulsive disorder (OCD).\n\nParticipants will:\n\nComplete self-report surveys, psychiatric interviews, and cognitive tasks.\n\nBe assigned to either a low- or moderate-intensity exercise condition and complete physical activity.\n\nRepeat cognitive and symptom measures following the exercise intervention.",[71],"Obsessive-Compulsive Disorder (OCD)",[73,74,75],"Anxiety Disorders","Mental Disorders","Obsessive-Compulsive Disorder","2026-06-30",{"date":78,"type":79},"2026-07-02","ACTUAL",{"date":81,"type":79},"2026-02-16",{"date":83,"type":65},"2026-09-01",{"name":5,"class":6},1]