[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100623143":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":19,"centralContacts":23,"locations":32,"responsibleParty":74,"collaborators":18,"id":76,"slug":18,"hasResults":77,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":81,"eligibilityCriteria":82,"healthyVolunteers":77,"sex":83,"minAge":18,"maxAge":18,"enrollmentInfo":84,"targetDuration":18,"studyType":87,"phases":88,"briefSummary":90,"conditions":91,"keywords":95,"overallStatus":103,"whyStopped":18,"lastUpdateSubmitDate":104,"lastUpdatePostDateStruct":105,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":113},{"fullName":5,"class":6},"University Hospital, Bordeaux","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"Patients starting long-term parenteral nutrition","Observational follow-up of patients starting long-term parenteral nutrition",[12],"Other: Non-invasive skin AGE measurements",[14],{"type":6,"name":15,"description":16,"armGroupLabels":17,"otherNames":18},"Non-invasive skin AGE measurements","Non-invasive skin AGE measurements at baseline, 6 and 12 months; collection and analysis of parenteral nutrition bag samples; routine metabolic assessments; dietary records, glucose holter, plasma glycated hemoglobin and fructosamine assays.",[9],null,[20],{"name":21,"affiliation":5,"role":22},"Florian POULLENOT, MD","PRINCIPAL_INVESTIGATOR",[24,28],{"name":21,"role":25,"phone":26,"phoneExt":18,"email":27},"CONTACT","+335 57 65 64 40","florian.poullenot@chu-bordeaux.fr",{"name":29,"role":25,"phone":30,"phoneExt":18,"email":31},"Raphaël ENAUD, MD","+335 56 79 98 24","raphael.enaud@chu-bordeaux.fr",[33,47,62],{"facility":34,"status":18,"city":35,"state":18,"zip":36,"country":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"CHU de Bordeaux-Hôpital des enfants GH Pellegrin","Bordeaux","33076","France",{"type":39,"coordinates":40},"Point",[41,42],-0.58046,44.84124,{"lat":42,"lon":41},[45,46],{"name":29,"role":25,"phone":30,"phoneExt":18,"email":31},{"name":29,"role":22,"phone":18,"phoneExt":18,"email":18},{"facility":48,"status":18,"city":49,"state":18,"zip":50,"country":37,"cosmosGeoPoint":51,"geoPoint":55,"contacts":56},"AP-HP - Hopital Robert Debré","Paris","75935",{"type":39,"coordinates":52},[53,54],2.3488,48.85341,{"lat":54,"lon":53},[57,61],{"name":58,"role":25,"phone":59,"phoneExt":18,"email":60},"Emmanuelle ECOCHARD-DUGELAY, MD","+331.87.89.16.46","emmanuelle.dugelay@aphp.fr",{"name":58,"role":22,"phone":18,"phoneExt":18,"email":18},{"facility":63,"status":18,"city":64,"state":18,"zip":65,"country":37,"cosmosGeoPoint":66,"geoPoint":70,"contacts":71},"CHU de Bordeaux - Hôpital Haut Lévêque","Pessac","33600",{"type":39,"coordinates":67},[68,69],-0.6324,44.80565,{"lat":69,"lon":68},[72,73],{"name":21,"role":25,"phone":26,"phoneExt":18,"email":27},{"name":21,"role":22,"phone":18,"phoneExt":18,"email":18},{"type":75,"investigatorFullName":18,"investigatorTitle":18,"investigatorAffiliation":18,"oldNameTitle":18,"oldOrganization":18},"SPONSOR","100623143",false,"NCT07392801","AGE Accumulation in Patients on Long-term Parenteral Nutrition","Study of Advanced Glycation End-products Accumulation in Patients Under Long-Term Parenteral Nutrition (NUPARAGE2)","NUPARAGE2","Inclusion Criteria:\n\n* Patients (adults and children, all ages) initiating long-term parenteral nutrition\n* Followed at CHU de Bordeaux or Robert Debré Hospital (APHP)\n* Covered by French Social Security system\n* Written informed consent obtained from patient (if adult) or legal guardian (if minor)\n\nExclusion Criteria:\n\n* Fitzpatrick skin type ≥ V (darker skin tones)\n* Forearm tattoos at the site of measurement\n* For patients included under 1 year of age: patients born prematurely (before 37 weeks of amenorrhea)\n* Pregnant or breastfeeding women.","ALL",{"count":85,"type":86},50,"ESTIMATED","INTERVENTIONAL",[89],"NA","This prospective and observational study aims to evaluate the accumulation of advanced glycation end-products (AGEs) in adult and pediatric patients starting long-term parenteral nutrition, by non-invasive skin AGE measurements over a 12-month follow-up.",[92,93,94],"Chronic Intestinal Insufficiency","Advanced Glycation and Products","Parenteral Nutrition",[96,97,98,99,100,101,102],"parenteral nutrition","Advanced Glycation End Products","Oxidative Stress","Metabolic Diseases","Cardiovascular Diseases","Short Bowel Syndrome","chronic intestinal insufficiency","NOT_YET_RECRUITING","2026-04-30",{"date":106,"type":107},"2026-05-06","ACTUAL",{"date":109,"type":86},"2026-05",{"date":111,"type":86},"2028-05",{"name":5,"class":6},3]