[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100639254":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":8,"locations":14,"responsibleParty":70,"collaborators":72,"id":86,"slug":7,"hasResults":87,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":91,"eligibilityCriteria":92,"healthyVolunteers":87,"sex":93,"minAge":94,"maxAge":7,"enrollmentInfo":95,"targetDuration":7,"studyType":98,"phases":7,"briefSummary":99,"conditions":100,"keywords":7,"overallStatus":110,"whyStopped":7,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":119,"locationsCount":120},{"fullName":5,"class":6},"Istituto Italiano di Tecnologia","OTHER",null,[9],{"name":10,"role":11,"phone":12,"phoneExt":7,"email":13},"Leonardo De Mattos, PhD","CONTACT","+39 010 2898 270","leonardo.demattos@iit.it",[15,35,53],{"facility":16,"status":7,"city":17,"state":18,"zip":19,"country":20,"cosmosGeoPoint":21,"geoPoint":26,"contacts":27},"UZ Leuven","Leuven","Flemish Brabant","3000","Belgium",{"type":22,"coordinates":23},"Point",[24,25],4.70093,50.87959,{"lat":25,"lon":24},[28,32],{"name":29,"role":11,"phone":30,"phoneExt":7,"email":31},"Vincent Vander Poorten, Prof. and ENT Surgeon","+32 16 33 23 42","vincent.vanderpoorten@uzleuven.be",{"name":33,"role":34,"phone":7,"phoneExt":7,"email":7},"Vincent Vander Poorten, MD PhD","PRINCIPAL_INVESTIGATOR",{"facility":36,"status":7,"city":37,"state":38,"zip":39,"country":40,"cosmosGeoPoint":41,"geoPoint":45,"contacts":46},"IRCCS Ospedale Policlinico San Martino","Genova","GE","16131","Italy",{"type":22,"coordinates":42},[43,44],11.87211,45.21604,{"lat":44,"lon":43},[47,51],{"name":48,"role":11,"phone":49,"phoneExt":7,"email":50},"Francesco Mora, Otorhinolaryngologist and Prof","+39 010-5557479","Francesco.Mora@unige.it",{"name":52,"role":34,"phone":7,"phoneExt":7,"email":7},"Francesco Mora, MD PhD",{"facility":54,"status":7,"city":55,"state":55,"zip":56,"country":57,"cosmosGeoPoint":58,"geoPoint":62,"contacts":63},"Hospital Clínic de Barcelona","Barcelona","08036","Spain",{"type":22,"coordinates":59},[60,61],2.15899,41.38879,{"lat":61,"lon":60},[64,68],{"name":65,"role":11,"phone":66,"phoneExt":7,"email":67},"Claudio Sampieri, Otorhinolaryngologist","+34 93 227 57 66","claudio.sampieri@outlook.com",{"name":69,"role":34,"phone":7,"phoneExt":7,"email":7},"Claudio Sampieri, MD PhD",{"type":71,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR",[73,75,78,80,82,84],{"name":74,"class":6},"Hospital Clinic of Barcelona",{"name":76,"class":77},"CRO \"Centro Clinical Trials\" IRCCS Ospedale Policlinico San Martino","UNKNOWN",{"name":79,"class":6},"Universitaire Ziekenhuizen KU Leuven",{"name":81,"class":6},"Università degli Studi 'G. d'Annunzio' Chieti e Pescara",{"name":83,"class":6},"Universita degli Studi di Genova",{"name":85,"class":6},"Scuola Superiore di Studi Universitari e di Perfezionamento Sant'Anna","100639254",false,"NCT07596355","AI-Assisted Endoscopy for Upper Aerodigestive Tract Lesions","Head&Neck Application of Novel Computer-assisted Endoscopy","H&NANCE","Inclusion Criteria:\n\n* Age \\> 18 years\n* Injury originating from the upper aero-digestive tract\n* Recording of the video-endoscopic examination\n* Patient known to undergo a biopsy of the lesion or clinical follow-up for lesion with known biopsy (e.g. laryngeal papillomatosis) or suffering from Reinke's edema (in this pathology, in fact, biopsy is not necessary since the diagnosis is clinical)\n* Or patients undergoing transoral lesion excision\n\nExclusion Criteria:\n\n* Submucosal lesion\n* Patients with previous operations on the upper aero-digestive tract\n* Patients with previous radiotherapy of the head and neck district\n* Poor compliance on endoscopic examination\n* Unavailability of CADe\u002FCADx or CASe data logging note","ALL","18 Years",{"count":96,"type":97},283,"ESTIMATED","OBSERVATIONAL","This is a prospective observational clinical study designed to evaluate the performance of artificial intelligence (AI) algorithms applied to upper aerodigestive tract (UADT) video-endoscopy. The study assesses three main tasks: lesion detection (localization), classification (benign vs malignant), and segmentation of tumor margins.\n\nAI algorithms will be applied to endoscopic video data acquired during routine clinical practice without influencing clinical decision-making. The system will process images in real time and store data for subsequent analysis. AI outputs will be compared with physician assessment and reference standard histopathology to evaluate diagnostic performance.",[101,102,103,104,105,106,107,108,109],"Upper Aerodigestive Tract Neoplasms","Upper AerodigestiveTract Cancer","Upper Aero-digestive Tract (UADT) Neoplasm","Squamous Cell Carcinoma","Leukoplakia","Head and Neck Cancer (H&N)","Vocal Cord Disease","Vocal Fold Polyp","Vocal Fold Nodules","NOT_YET_RECRUITING","2026-05-12",{"date":113,"type":114},"2026-05-19","ACTUAL",{"date":116,"type":97},"2026-05",{"date":118,"type":97},"2028-02",{"name":5,"class":6},3]