Health Trials

About this trial

The investigators analyze the impact of exercise and ablation in patients with symptomatic short-persistent atrial fibrillation (Afib) and heart failure with preserved ejection fraction (HFpEF). It is hypothesized that the combination of ablation and exercise better improves peak oxygen consumption (VO2peak) through improvement of peripheral (exercise training) and central (ablation) adaptations.

Exercise intervention will contain a 12-week combined, video-based, supervised, endurance, resistance and respiratory training.

Eligibility criteria

Qualifiers

Diagnosed heart failure with preserved ejection fraction

Symptomatic short-persistent atrial fibrillation (diagnosis within 1 year of study inclusion)

Disqualifiers

Paroxysmal, long-persistent or permanent atrial fibrillation

Clinically unstable coronary artery disease or acute coronary syndrome

Physical and/or mental inability to perform exercise testing

Prior ablation therapy

Trial design

Treatments tested in this trial

  • Exercise training

Treatment groups

40 Participants
are divided into 2 treatment groups

Locations

1
Department of Medicine, Division of Prevention and Sports Medicine TU Munich80809, Munich Germany

Sponsors and collaborators

Technical University of Munich

Lead sponsor

Source ClinicalTrials.gov