An International, Multicenter, Prospective Registry on Post-traumatic Long Bones Defects

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAO Innovation Translation Center

About this trial

Long bone defect (LBD) is defined as a focalized loss of bone tissue in any long bone of the upper or lower extremity. Long bone defects are a complex problem, that may arise as a complication of many different pathologies, such as trauma, tumors or infection. Whereas post-traumatic defects are the largest group.

Reports estimate that there are almost 4 million bone grafting procedures worldwide per year. However, limb reconstruction in the context of a bony defect is challenging and up to date there is little evidence and treatment recommendations.

In a multi-national approach, the aim of this project is to set up an international, multicenter registry to gather information and details on prevalence or incidence, current treatments, complications and outcome.

Eligibility criteria

Qualifiers

Age ≥ 18 years

Skeletally mature

Post traumatic bone defect > 2 cm either

initially after injury or

Disqualifiers

Any oblique defect that has less than 8cm expansion when adding the defect size of all four cortices

Any not medically managed severe systemic disease

Pregnancy

Prisoners

Trial design

Treatments tested in this trial

  • Any treatment that is used for a defect of any long bone

Treatment groups

No treatment groups listed

Locations

21
Australia
John Hunter Hospital2310, Newcastle Australia
Brazil
Hospital Municipal Miguel Couto Serviço de Ortopedia e Traumatologia22430-160, Rio de Janeiro Brazil
Chile
Hospital Base Valdivia5090146, Valdivia Chile
Colombia
Hospital Universitario de la Samaritana110411, Bogotá Colombia

Sponsors and collaborators

AO Innovation Translation Center

Lead sponsor