[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100589369":3},{"organization":4,"outcomesModule":7,"designInfo":28,"detailedDescription":34,"studyPopulation":16,"armGroups":35,"interventions":41,"overallOfficials":16,"centralContacts":46,"locations":52,"responsibleParty":68,"collaborators":16,"id":70,"slug":16,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":73,"acronym":16,"eligibilityCriteria":74,"healthyVolunteers":75,"sex":76,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":16,"studyType":82,"phases":83,"briefSummary":84,"conditions":85,"keywords":87,"overallStatus":89,"whyStopped":16,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Qualia Life Sciences","INDUSTRY",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":16},[9],{"measure":10,"description":11,"timeFrame":12},"Olink Target 48 Cytokine panel - TNF, IL1B, CXCL8, VEGFA","Biomarkers in blood, measured using the Olink Target 48 Cytokine panel:\n\nTumor Necrosis Factor (TNF) Interleukin-1 Beta (IL1B) Interleukin-8 (CXCL8) Vascular Endothelial Growth Factor A (VEGFA)","1 week",[14,17,19,21,23,25],{"measure":15,"description":16,"timeFrame":12},"Remaining biomarkers in the Olink Target 48 Cytokine panel",null,{"measure":18,"description":16,"timeFrame":12},"36-Item Short Form Health Survey (SF-36)",{"measure":20,"description":16,"timeFrame":12},"Frailty Index for Elders (FIFE)",{"measure":22,"description":16,"timeFrame":12},"Depression Anxiety Stress Scale-21 (DASS-21)",{"measure":24,"description":16,"timeFrame":12},"Aging Male\u002FFemale Symptom scale",{"measure":26,"description":27,"timeFrame":12},"Side effect profile as measured by a custom Safety and Tolerability survey","Number of participants with treatment-related adverse events as assessed by a score of 3 or greater on the Safety and Tolerability survey",{"allocation":29,"interventionModel":30,"interventionModelDescription":16,"primaryPurpose":31,"observationalModel":16,"timePerspective":16,"maskingInfo":32},"NA","SINGLE_GROUP","BASIC_SCIENCE",{"masking":33,"maskingDescription":16,"whoMasked":16},"NONE","Objectives Within-group changes in outcomes will be compared from baseline to the end of the study period.\n\nPrimary Outcome Measures:\n\nBiomarkers in blood, measured using the Olink Target 48 Cytokine panel:\n\nTumor Necrosis Factor (TNF) Interleukin-1 Beta (IL1B) Interleukin-8 (CXCL8) Vascular Endothelial Growth Factor A (VEGFA)\n\nSecondary Outcome Measures:\n\nRemaining biomarkers in the Olink Target 48 Cytokine panel 36-Item Short Form Health Survey (SF-36) Frailty Index for Elders (FIFE) Depression Anxiety Stress Scale-21 (DASS-21)\n\nSide effect profile including:\n\nNumber, type, severity, causality, and outcome of adverse events or unanticipated problems\n\nSymptoms of aging, assessed by:\n\nAging Male Symptom scale Aging Female Symptom scale\n\nParticipant Details:\n\nStudy Duration per Participant: 7 days Total Number of Participants: 40",[36],{"label":37,"type":38,"description":16,"interventionNames":39},"Qualia Senolytic","ACTIVE_COMPARATOR",[40],"Dietary Supplement: Qualia Senolytic",[42],{"type":43,"name":37,"description":44,"armGroupLabels":45,"otherNames":16},"DIETARY_SUPPLEMENT","Qualia Senolytic manufactured by Qualia Life Science",[37],[47],{"name":48,"role":49,"phone":50,"phoneExt":16,"email":51},"William Scuba","CONTACT","855-281-2328","support@qualialife.com",[53],{"facility":5,"status":16,"city":54,"state":55,"zip":56,"country":57,"countryCode":58,"cosmosGeoPoint":59,"geoPoint":64,"contacts":65},"Carlsbad","California","92011","United States","US",{"type":60,"coordinates":61},"Point",[62,63],-117.35059,33.15809,{"lat":63,"lon":62},[66],{"name":67,"role":49,"phone":50,"phoneExt":16,"email":51},"Abhi Argagh",{"type":69,"investigatorFullName":16,"investigatorTitle":16,"investigatorAffiliation":16,"oldNameTitle":16,"oldOrganization":16},"SPONSOR","100589369",false,"NCT06953518","An Open-Label Pilot Study of Qualia Senolytic Supplementation for the Attenuation of Systemic Inflammatory Cytokines","Inclusion Criteria:\n\n* Provide voluntary, written, informed consent to participate in the study\n* Agree to provide a valid cell phone number and are willing to receive communications through text.\n* Healthy adults 45 - 79 years of age Can read and write English\n* Willing to not begin taking any new supplements during the study and continue taking any supplements they are currently using regularly.\n* Willing to self-administer the fingerstick test kit at home for both a baseline and post-intervention blood sample, and to complete a release form that gives NHC access to the results of these tests.\n* Willing to complete questionnaires, records, and diaries associated with the study.\n\nExclusion Criteria:\n\n* Women who are pregnant, breastfeeding, or planning to become pregnant during the trial\n* Known food intolerances\u002Fallergy to any ingredients in the product\n* Having any of the following conditions: Psychiatric conditions, neurologic disorders, endocrine disorders, cancer\n* Having had a significant cardiovascular event in the past 6 months\n* Taking MAO inhibitors, SSRIs, or any other psychiatric or neurological medicines\n* On immunosuppressive therapy\n* Individuals who were deemed incompatible with the test protocol\n* Adults lacking capacity to consent",true,"ALL","45 Years","79 Years",{"count":80,"type":81},40,"ESTIMATED","INTERVENTIONAL",[29],"This open-label pilot study includes adults aged 45 to 79 residing in the United States. The study will last 7 days. Participants will provide blood samples via an at-home finger-prick kit at baseline and day 7 and complete electronic surveys on health indicators at baseline, and days 3 and 7. All procedures are conducted remotely, with no in-person visits, to collect real-world evidence.",[86],"Inflammation",[88],"Senolytic","NOT_YET_RECRUITING","2025-04-23",{"date":92,"type":93},"2025-05-01","ACTUAL",{"date":95,"type":81},"2025-05-12",{"date":97,"type":81},"2025-05-18",{"name":5,"class":6},1]