[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100550545":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":13,"locations":19,"responsibleParty":36,"collaborators":10,"id":39,"slug":10,"hasResults":40,"nctId":41,"briefTitle":42,"officialTitle":42,"acronym":10,"eligibilityCriteria":43,"healthyVolunteers":44,"sex":45,"minAge":46,"maxAge":47,"enrollmentInfo":48,"targetDuration":10,"studyType":51,"phases":10,"briefSummary":52,"conditions":53,"keywords":10,"overallStatus":22,"whyStopped":10,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":64},{"fullName":5,"class":6},"Second Affiliated Hospital of Nanchang University","OTHER",[8,11],{"label":9,"type":10,"description":10,"interventionNames":10},"dry group",null,{"label":12,"type":10,"description":10,"interventionNames":10},"Non dry eye group",[14],{"name":15,"role":16,"phone":17,"phoneExt":10,"email":18},"yifeng yu","CONTACT","13979180258","171018170@qq.com",[20],{"facility":21,"status":22,"city":23,"state":24,"zip":25,"country":26,"cosmosGeoPoint":27,"geoPoint":32,"contacts":33},"Yifeng Yu","RECRUITING","Nanchang","Jiangxi","330008","China",{"type":28,"coordinates":29},"Point",[30,31],115.85306,28.68396,{"lat":31,"lon":30},[34],{"name":15,"role":16,"phone":35,"phoneExt":10,"email":18},"+8613979180258",{"type":37,"investigatorFullName":21,"investigatorTitle":38,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Deputy chief physician of Ophthalmology center of the Second Affiliated Hospital of Nanchang University","100550545",false,"NCT06448468","Analysis of Ocular Surface Microbiota in Dry Eye Patients After Femtosecond Laser-assisted In-situ Keratomileusis (FS-LASIK)","Inclusion Criteria:\n\n1. Age ≥ 18 years old;\n2. Stable refractive index (refractive index change less than 0.5D in the past 2 years);\n3. The best corrected far vision (CDVA) is 1.0 or better;\n4. Postoperative dry eye patients need to meet the following criteria: Patient's Eye Surface Disease Index (OSDI) ≥ 13 and two of the following three criteria are met: Tear film rupture time (BUT) ≤ 10S Schirmer I test (mm\u002F5min) ≤ 10mm, corneal fluorescein sodium staining exceeding 5 spots;\n\nExclusion Criteria:\n\n1. History of eye trauma or surgery;\n2. Suspected keratoconus;\n3. Previously suffering from other eye diseases such as keratitis or edema, glaucoma, uveitis, retinal detachment, macular degeneration, cataracts, amblyopia, etc.;\n4. Preoperative history of severe dry eye disease;\n5. Patients with systemic diseases, such as hyperthyroidism or autoimmune diseases; Or severe mental disorders, such as anxiety and depression;",true,"ALL","18 Years","45 Years",{"count":49,"type":50},200,"ESTIMATED","OBSERVATIONAL","By using 16S rRNA sequencing technology to analyze the changes in ocular surface microbiota before and after surgery, as well as the impact of changes in ocular surface microbiota on FS-LASIK induced DES, new treatment ideas are provided for corneal FS-LASIK induced DES patients, and the incidence of FS-LASIK related DES is reduced.",[54],"Refractive Surgery","2024-07-29",{"date":57,"type":58},"2024-07-31","ACTUAL",{"date":60,"type":58},"2024-05-01",{"date":62,"type":50},"2024-11-01",{"name":5,"class":6},1]