Anastomotic Leakage After Colorectal Surgery.
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorMinia University
About this trial
Anastomotic leakage (AL) is a severe complication after colorectal surgery, with incidence rates of 2-30%. This prospective, single-center observational cohort study aims to identify and quantify independent risk factors for AL, determine its incidence and impact on outcomes, and develop a predictive model. Approximately 430 patients undergoing colorectal resection with anastomosis will be enrolled from August 2025 to August 2026. Risk factors will be assessed preoperatively, intraoperatively, and postoperatively. AL will be defined and graded per the International Study Group of Rectal Cancer (ISGRC) criteria.
Eligibility criteria
Qualifiers
Aged ≥18 years
Undergoing elective or emergency colorectal resection with primary anastomosis (e.g., ileocolic, colocolic, colorectal, coloanal)
Providing written informed consent
Disqualifiers
Colorectal resection without anastomosis (e.g., end stoma)
Inflammatory bowel disease (Crohn's, ulcerative colitis)
History of previous colorectal surgery involving anastomosis
Pregnancy
Trial design
Treatments tested in this trial
- Patients Undergoing Colorectal Resection with Anastomosis
Treatment groups
430 Participants
are divided into 1 treatment groupLocations
1Minia University Hospital61519, MinyaMinya Governorate, Egypt
Sponsors and collaborators
Minia University
Lead sponsor
Source ClinicalTrials.gov