[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100525632":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":18,"centralContacts":25,"locations":33,"responsibleParty":67,"collaborators":69,"id":74,"slug":10,"hasResults":75,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":10,"eligibilityCriteria":79,"healthyVolunteers":75,"sex":80,"minAge":81,"maxAge":82,"enrollmentInfo":83,"targetDuration":86,"studyType":87,"phases":10,"briefSummary":88,"conditions":89,"keywords":93,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":104},{"fullName":5,"class":6},"University of California, San Francisco","OTHER",[8,12,15],{"label":9,"type":10,"description":11,"interventionNames":10},"MASLD and PCOS hyperandrogenism",null,"Patients with MASLD and PCOS with the phenotype of hyperandrogenism",{"label":13,"type":10,"description":14,"interventionNames":10},"MASLD and PCOS non-hyperandrogenism","Patients with MASLD and PCOS with the phenotype of non-hyperandrogenism",{"label":16,"type":10,"description":17,"interventionNames":10},"MASLD and no-PCOS","Patients with metabolic dysfunction-associated steatotic liver disease (MASLD) and no PCOS",[19,22],{"name":20,"affiliation":5,"role":21},"Monika A Sarkar, M.D., M.A.S","PRINCIPAL_INVESTIGATOR",{"name":23,"affiliation":24,"role":21},"Amreen Dinani, MD","Duke University",[26,31],{"name":27,"role":28,"phone":29,"phoneExt":10,"email":30},"Lily C Carbullido, B.S.","CONTACT","415-502-3725","myliverhealth@ucsf.edu",{"name":32,"role":28,"phone":10,"phoneExt":10,"email":10},"Jasmine Gamez",[34,53],{"facility":35,"status":36,"city":37,"state":38,"zip":39,"country":40,"cosmosGeoPoint":41,"geoPoint":46,"contacts":47},"University of California San Francisco","RECRUITING","San Francisco","California","94143","United States",{"type":42,"coordinates":43},"Point",[44,45],-122.41942,37.77493,{"lat":45,"lon":44},[48,49],{"name":27,"role":28,"phone":29,"phoneExt":10,"email":30},{"name":50,"role":28,"phone":51,"phoneExt":10,"email":52},"Jasmine Gamez, B.S.","415-353-9240","jasmine.gamez@ucsf.edu",{"facility":24,"status":54,"city":55,"state":56,"zip":57,"country":40,"cosmosGeoPoint":58,"geoPoint":62,"contacts":63},"NOT_YET_RECRUITING","Durham","North Carolina","27708",{"type":42,"coordinates":59},[60,61],-78.89862,35.99403,{"lat":61,"lon":60},[64],{"name":65,"role":28,"phone":10,"phoneExt":10,"email":66},"Linda Perry, R.N.","linda.blalock@duke.edu",{"type":68,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[70,71],{"name":24,"class":6},{"name":72,"class":73},"National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)","NIH","100525632",false,"NCT06124261","Androgens and NAFLD Longitudinal Cohort Study","Androgens and Nonalcoholic Fatty Liver Disease (NAFLD) In Reproductive-Aged Women With and Without Polycystic Ovary Syndrome (PCOS)","Inclusion Criteria:\n\n* Metabolic associated steatohepatitis (MASH) (formerly NASH)\n* PCOS\n* Non-PCOS\n\nExclusion Criteria:\n\n* High levels of alcohol use (more than 7 drinks a week)\n* Current pregnancy\n* Other causes of hepatic steatosis\n* Weight loss of more than 10% body weight in the last 6 months","FEMALE","18 Years","42 Years",{"count":84,"type":85},150,"ESTIMATED","3 Years","OBSERVATIONAL","The researchers want to learn how androgens, a type of sex hormone, might affect nonalcoholic fatty liver (NAFLD) in young women over time. NAFLD happens when fat builds up in the liver which can cause damage to the liver such as inflammation or scarring.\n\nYoung women with a condition called polycystic ovary syndrome (PCOS) have a high risk for NAFLD, and they often have high androgen levels too. So the researchers are recruiting young women with PCOS as well as those without PCOS, and will compare changes in NAFLD over time between young women with and without PCOS.\n\nThis study is funded by the National Institutes of Health",[90,91,92],"PCOS","NAFLD","NASH",[94],"Androgen","2026-04-09",{"date":97,"type":98},"2026-04-13","ACTUAL",{"date":100,"type":98},"2024-01-22",{"date":102,"type":85},"2028-12",{"name":5,"class":6},2]