Anesthesia Modality and Oncologic Outcomes in High-Risk NMIBC: A Randomized Trial

ConditionsNMIBC TURBT Bladder (Urothelial, Transitional Cell) Cancer Bladder Cancer Recurrence Anesthesia, General Anesthesia,Spinal

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age20-80

SponsorNational Taiwan University Hospital

About this trial

To demonstrate the superior efficacy of spinal anesthesia (SA) versus general anesthesia (GA) according to the delay of time to recurrence in high-risk NMIBC patients up to Week 104 after TURBT.

Eligibility criteria

Qualifiers

Age ≥40 years for male subjects or postmenopausal female subjects

ECOG performance status 0-2

Patients with suspected or newly diagnosed UBUC

ASA I or II

Disqualifiers

Patients with prior or concurrent UC involving the renal pelvis, ureter or urethra

Patients with clinical evidence of MIBC or mUC

Immunocompromised or immunosuppressed patients

Patients with chronic use of anti-inflammatory agents or beta-blockers

Trial design

Treatments tested in this trial

Spinal Anesthesia
General Anesthesia

Treatment groups

370 Participants

are divided into 2 treatment groups

Locations

Department of Urology, College of Medicine, National Taiwan University100, TaipeiTaipei, Taiwan

Sponsors and collaborators

National Taiwan University Hospital

Lead sponsor

Source ClinicalTrials.gov