Health Trials

About this trial

The goal of this observational study is to study arterial stiffness in patients with thoracic ascending aortic aneurysms (TAA), either syndromic or non-syndromic. The main questions it aims to answer are:

* Stratification of aortic risk based on arterial stiffness; Compare measurements with morphological and haemodynamic features of the ascending thoracic aorta.

Participants will be asked to undergo non-invasive evaluation of blood pressure and arterial stiffness.

Eligibility criteria

Qualifiers

Subjects with AAT, either syndromic or non syndromic;

Signed informed consent

Disqualifiers

Patients with early menopause and/or osteoporosis, rheumatic heart disease and active malignant tumours;

Patients with acute and chronic inflammatory conditions such as: chronic liver disease, chronic renal insufficiency and diseases affecting the thyroid system;

Seropositivity to HIV, HCV, HBsAg and SARS-CoV-2;

Pregnancy

Trial design

Treatments tested in this trial

  • Pulsotonometry

Treatment groups

250 Participants
are divided into 2 treatment groups

Locations

1
IRCCS Policlinico San Donato20097, San Donato MilaneseLombardy, Italy

Sponsors and collaborators

IRCCS Policlinico S. Donato

Lead sponsor

Istituto Auxologico Italiano

Collaborator

Source ClinicalTrials.gov