[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100506964":3},{"organization":4,"outcomesModule":7,"designInfo":14,"detailedDescription":17,"studyPopulation":18,"armGroups":19,"interventions":13,"overallOfficials":13,"centralContacts":23,"locations":33,"responsibleParty":51,"collaborators":13,"id":55,"slug":13,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":58,"acronym":13,"eligibilityCriteria":59,"healthyVolunteers":60,"sex":61,"minAge":13,"maxAge":13,"enrollmentInfo":62,"targetDuration":65,"studyType":66,"phases":13,"briefSummary":67,"conditions":68,"keywords":13,"overallStatus":36,"whyStopped":13,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"The First Hospital of Jilin University","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":13,"otherOutcomes":13},[9],{"measure":10,"description":11,"timeFrame":12},"mRS score in 90 days","The proportion of 3-month good functional outcome (mRS Score 0-2) in patients with neurological diseases was evaluated by mRS Score","3 months",null,{"allocation":13,"interventionModel":13,"interventionModelDescription":13,"primaryPurpose":13,"observationalModel":15,"timePerspective":16,"maskingInfo":13},"COHORT","PROSPECTIVE","With the rise and continuous development of omics technology and bioinformatics technology, some scholars have applied proteomics technology and metabolomics technology to study the brain tissue, plasma and CSF of patients with nervous system diseases, so as to screen out potential biomarkers, with a view to providing new research ideas for pathogenesis and early diagnosis of neurological diseases. At present, the research on some novel biomarkers is still in its infancy, and many key problems remain to be solved. It is necessary to further determine the expression level of biomarkers in normal human body and the characteristics of biomarkers in patients with neurological diseases.","Patients with neurological diseases admitted to hospital\u002Femergency department.",[20],{"label":21,"type":13,"description":22,"interventionNames":13},"Patients admitted to hospital\u002Femergency department with neurological diseases","All clinical data, laboratory data and imaging data of patients at baseline and follow-up were collected, as well as blood and tissue samples that did not affect the diagnosis and treatment of patients after obtaining the consent of patients at different time points in the acute and chronic phases.",[24,30],{"name":25,"role":26,"phone":27,"phoneExt":28,"email":29},"Yi YY Yang, Ph.D.","CONTACT","18186872986","86","doctoryangyi@163.com",{"name":31,"role":26,"phone":27,"phoneExt":28,"email":32},"Zhen-Ni GZ GUO, M.D.","zhen1ni2@163.com",[34],{"facility":35,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"First Hospital of Jilin University","RECRUITING","Changchun","Jilin","130000","China","CN",{"type":43,"coordinates":44},"Point",[45,46],125.32278,43.88,{"lat":46,"lon":45},[49],{"name":50,"role":26,"phone":13,"phoneExt":13,"email":29},"Yi Yang, MD, PhD",{"type":52,"investigatorFullName":53,"investigatorTitle":54,"investigatorAffiliation":5,"oldNameTitle":13,"oldOrganization":13},"SPONSOR_INVESTIGATOR","Yi Yang","Associated Dean of First Hospital of Jilin University","100506964",false,"NCT05881226","Application of Biomarkers in Neurological Diseases","Inclusion Criteria:\n\n1. Patients with neurological diseases;\n2. Subjects or legal agents agree to participate in the study and sign the informed consent.\n\nExclusion Criteria:\n\n1. Participating in other clinical investigators;\n2. Unwilling to be followed up or poor treatment compliance;\n3. Other conditions considered unsuitable for inclusion by the researchers.",true,"ALL",{"count":63,"type":64},3000,"ESTIMATED","1 Year","OBSERVATIONAL","To explore the predictive and diagnostic role of biomarkers in patients with neurological diseases.",[69],"Biomarkers","2024-02-28",{"date":72,"type":73},"2024-03-01","ACTUAL",{"date":75,"type":73},"2023-06-05",{"date":77,"type":64},"2031-12-01",{"name":53,"class":6},1]