About this trial

This is a multi-site clinical study enrolling 2000 newly diagnosed patients with breast, colorectal, melanoma, non-Hodgkin lymphoma, or non-small cell lung cancer, who are planning to receive one or more systemic cancer directed therapies with chemotherapy and/or (immune checkpoint inhibitors) ICIs.

Eligibility criteria

Qualifiers

Adults aged 18 years or older with one of the following newly diagnosed cancers: breast cancer, colorectal cancer, melanoma, non-Hodgkin lymphoma, or non-small cell lung cancer (e.g. adenocarcinoma, squamous cell carcinoma, large cell carcinoma, adenosquamous cell carcinoma, and not otherwise specified).

Planned treatment with systemic chemotherapy (single or multi-agent, includes targeted therapy) and/or immune checkpoint inhibitor therapy (targeting PD-1, PD-L1 or CTLA-4). If unable to engage participant before treatment starts, enrollment is allowed up to the start of Cycle 2 treatment.

Participants must be able to comprehend English or Spanish (for survey completion).

Participants must have a working email address and be must be willing to complete surveys online. This can be completed at home, in the clinic or other location.

Disqualifiers

Currently enrolled in an interventional supportive treatment trial to manage cancer symptoms.

Participants with known pregnancy.

Participant received systemic therapy treatment for prior cancer(s) including chemotherapy, immunotherapy, targeted therapy, and hormonal therapy.

Participants enrolled in hospice.

Trial design

Treatments tested in this trial

  • Non-interventional Study

Treatment groups

2,000 Participants
are divided into 1 treatment group

Locations

467
Puerto Rico
Doctors Cancer Center00674, ManatiPR, Puerto Rico
PROncology00927, San JuanPR, Puerto Rico
Centro Comprensivo de Cancer de UPR00927, San Juan Puerto Rico
United States
Alaska
Fairbanks Memorial Hospital99701, Fairbanks United States

Sponsors and collaborators

Wake Forest University Health Sciences

Lead sponsor

National Cancer Institute (NCI)

Collaborator