The goals of this project are to build an experimental tool to dissect out in vivo pancreatic beta cell mass (BCM) and beta cell function (BCF) and to assess for the first time these two determinants of beta cell functional mass (BCFxM) in obesity and in various stages of type 1 and type 2 diabetes mellitus.
Age ≥18 years; ≤ 75 years
Both sexes
Good health
Absence of
Able to understand methods, goals, and implications of the research and of delivering a free, written informed consent
Hemoglobin < 12 g/dl
HbA1c > 10%
Pregnancy or breast-feeding
7
Treatment groupsSee each treatment group below.
Azienda Ospedaliero-Universitaria di Parma
Lead sponsor
University of Parma
Collaborator