[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100632380":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":21,"responsibleParty":38,"collaborators":41,"id":44,"slug":10,"hasResults":45,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":45,"sex":51,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":10,"studyType":57,"phases":10,"briefSummary":58,"conditions":59,"keywords":63,"overallStatus":24,"whyStopped":10,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":82},{"fullName":5,"class":6},"West Kazakhstan Marat Ospanov Medical University","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Group\u002FCohort Label T2DM without EPI by fecal elastase-1",null,"Adults with type 2 diabetes mellitus classified as not having exocrine pancreatic insufficiency according to fecal elastase-1 levels.",{"label":13,"type":10,"description":14,"interventionNames":10},"Group\u002FCohort Label T2DM without EPI by PEI-Q","Adults with type 2 diabetes mellitus classified as not having exocrine pancreatic insufficiency according to Pancreatic Exocrine Insufficiency Questionnaire (PEI-Q) results.",[16],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Mengtay S Makashova","CONTACT","+77058440060","ersultanbeknur@gmail.com",[22],{"facility":23,"status":24,"city":25,"state":25,"zip":26,"country":27,"cosmosGeoPoint":28,"geoPoint":33,"contacts":34},"Outpatient clinics of Aktobe region, West Kazakhstan Marat Ospanov Medical University","RECRUITING","Aktobe","030019","Kazakhstan",{"type":29,"coordinates":30},"Point",[31,32],57.20718,50.27969,{"lat":32,"lon":31},[35],{"name":36,"role":18,"phone":37,"phoneExt":10,"email":20},"Mengtay Makashova","87058440060",{"type":39,"investigatorFullName":36,"investigatorTitle":40,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","phd candidate",[42],{"name":43,"class":6},"Universitatea de Stat de Medicina si Farmacie Nicolae Testemiţanu","100632380",false,"NCT07512934","Assessment of Pancreatic Dysfunction in Patients With Type 2 Diabetes","Integrated Assessment of Pancreatic Dysfunction in Patients With Type 2 Diabetes: a Cross-sectional Study Protocol","T3cDM-AKT","Inclusion Criteria:\n\n* • adult patients of Kazakh nationality aged 18 to 74 years\n* diagnosis of T2DM established according to ADA criteria and documented in medical records\n* disease duration ≤5 years\n* absence of ketoacidosis episodes within the last 6 months\n\nExclusion Criteria:\n\n* positive anti-glutamic acid decarboxylase antibodies (anti-GAD65);\n* acute or chronic infections affecting metabolic status within the previous 4 weeks;\n* any history of malignant neoplasms;\n* pregnancy or lactation;\n* previously diagnosed type 1 diabetes mellitus or other specific types of diabetes;\n* severe decompensated chronic diseases;\n* conditions associated with systemic fibrosis (e.g., liver cirrhosis or autoimmune diseases);\n* refusal to participate.","ALL","18 Years","74 Years",{"count":55,"type":56},310,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to better understand how the pancreas works in adults with type 2 diabetes. The study focuses on both hormone production (endocrine function) and digestive function (exocrine function) of the pancreas.\n\nThe main questions it aims to answer are:\n\n* Can problems with the pancreas help identify a different type of diabetes called pancreatogenic diabetes?\n* How are blood markers and pancreas structure related to pancreatic function?\n\nParticipants will:\n\n* Have blood tests to measure glucose, insulin, and other markers\n* Provide a stool sample to assess digestive function\n* Undergo an ultrasound examination of the pancreas\n* Answer questions about digestive symptoms\n\nThe study will take place during a single visit in outpatient clinics.",[60,61,62],"Pancreatogenic Diabetes Mellitus","Type 2 Diabetes Mellitus (T2DM)","Exocrine Pancreatic Insufficiency (EPI)",[64,65,66,67,68,69,70,71,72],"Type 3c diabetes","Pancreatogenic diabetes","Fecal elastase-1","TGF-beta1","Adiponectin","IL-1 receptor antagonist","Pancreatic ultrasound","PEI-Q","Type 2 Diabetes Mellitus","2026-04-02",{"date":75,"type":76},"2026-04-06","ACTUAL",{"date":78,"type":76},"2025-07-07",{"date":80,"type":56},"2026-12-01",{"name":5,"class":6},1]