[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100574464":3},{"organization":4,"outcomesModule":7,"designInfo":65,"detailedDescription":64,"studyPopulation":64,"armGroups":70,"interventions":81,"overallOfficials":64,"centralContacts":87,"locations":93,"responsibleParty":108,"collaborators":64,"id":112,"slug":64,"hasResults":113,"nctId":114,"briefTitle":115,"officialTitle":115,"acronym":64,"eligibilityCriteria":116,"healthyVolunteers":113,"sex":117,"minAge":118,"maxAge":64,"enrollmentInfo":119,"targetDuration":64,"studyType":122,"phases":123,"briefSummary":125,"conditions":126,"keywords":64,"overallStatus":96,"whyStopped":64,"lastUpdateSubmitDate":128,"lastUpdatePostDateStruct":129,"startDateStruct":132,"completionDateStruct":134,"leadSponsor":136,"locationsCount":137},{"fullName":5,"class":6},"Medical University of Gdansk","OTHER",{"primaryOutcomes":8,"secondaryOutcomes":64,"otherOutcomes":64},[9,13,16,19,22,25,29,33,37,40,43,46,49,52,55,58,61],{"measure":10,"description":11,"timeFrame":12},"Heart rate (HR)","HR will be measured by ecg in beat per minute","Continuously during whole duration of anesthesia",{"measure":14,"description":15,"timeFrame":12},"Pulse oximetry (SpO2)","SpO2 will be measured by light spectrometry percutaneous sensor in %",{"measure":17,"description":18,"timeFrame":12},"End tidal CO2 (etCO2)","etCO2 will be measured by capnography with infrared radiation sensor in mmHg. Sensor will be attached to breathing circuit.",{"measure":20,"description":21,"timeFrame":12},"Minimum alveolar concentration (MAC)","MAC will be measured based on exhaled anesthetic gas concentration in absolute numbers",{"measure":23,"description":24,"timeFrame":12},"Bispectral index (BIS)","BIS will be measured with Covidien BIS monitoring system in absolute numbers",{"measure":26,"description":27,"timeFrame":28},"Train of for (TOF)","TOF will be measured in absolute numbers","Every 2.5 minutes during whole duration of anesthesia",{"measure":30,"description":31,"timeFrame":32},"Non invasive blood pressure (NIBP)","NIBP will be measured with oscillometric method in mmHG","Every 5 minutes during whole duration of anesthesia",{"measure":34,"description":35,"timeFrame":36},"Forced vital capacity (FVC)","FVC will be measured with spirometry","3 months before the surgery and 10 and 30 minutes after the emergence from general anesthesia",{"measure":38,"description":39,"timeFrame":36},"Volume that has been exhaled at the end of the first second of forced expiration (FEV1)","FEV1 will be measured with spirometry",{"measure":41,"description":42,"timeFrame":36},"Mid-expiratory flow; the rates at 25% FVC (MEF25)","MEF25 will be measured with spirometry",{"measure":44,"description":45,"timeFrame":36},"Mid-expiratory flow; the rates at 25% FVC (MEF50)","MEF50 will be measured with spirometry",{"measure":47,"description":48,"timeFrame":36},"Peak expiratory flow (PEF)","PEF will be measured with spirometry",{"measure":50,"description":51,"timeFrame":36},"Respiratory input impedance (Zrs)","Zrs will be measured with impulsed oscillometry",{"measure":53,"description":54,"timeFrame":36},"Resistive component (Rrs)","Rrs will be measured with impulsed oscillometry",{"measure":56,"description":57,"timeFrame":36},"Reactive component (Xrs)","Xrs will be measured with impulsed oscillometry",{"measure":59,"description":60,"timeFrame":36},"Resonant frequency (Fres)","Fres will be measured with impulsed oscillometry",{"measure":62,"description":63,"timeFrame":36},"Area of reactance (Ax)","Ax will be measured with impulsed oscillometry",null,{"allocation":66,"interventionModel":67,"interventionModelDescription":64,"primaryPurpose":6,"observationalModel":64,"timePerspective":64,"maskingInfo":68},"RANDOMIZED","PARALLEL",{"masking":69,"maskingDescription":64,"whoMasked":64},"NONE",[71,77],{"label":72,"type":73,"description":74,"interventionNames":75},"General anesthesia with desflurane","EXPERIMENTAL","Patients undergoing anesthesia for bariatric surgery with desflurane as a volatile agent.",[76],"Drug: Different drug type for conduction of general anesthesia",{"label":78,"type":73,"description":79,"interventionNames":80},"General anesthesia with sevoflurane","Patients undergoing anesthesia for bariatric surgery with sevoflurane as a volatile agent.",[76],[82],{"type":83,"name":84,"description":85,"armGroupLabels":86,"otherNames":64},"DRUG","Different drug type for conduction of general anesthesia","Patients will be randomly divided into two groups: patients for whom general anesthesia will be performed with sevoflurane and patients for whom general anesthesia will be performed with desflurane.",[72,78],[88],{"name":89,"role":90,"phone":91,"phoneExt":64,"email":92},"Karolina Obara, MD","CONTACT","0048 58 349 32 80","kobara@uck.gda.pl",[94],{"facility":95,"status":96,"city":97,"state":64,"zip":64,"country":98,"countryCode":99,"cosmosGeoPoint":100,"geoPoint":105,"contacts":106},"University Clinical Center","RECRUITING","Gdansk","Poland","PL",{"type":101,"coordinates":102},"Point",[103,104],18.64912,54.35227,{"lat":104,"lon":103},[107],{"name":89,"role":90,"phone":91,"phoneExt":64,"email":92},{"type":109,"investigatorFullName":110,"investigatorTitle":111,"investigatorAffiliation":5,"oldNameTitle":64,"oldOrganization":64},"PRINCIPAL_INVESTIGATOR","Radosław Owczuk","Prof. dr hab.","100574464",false,"NCT06759623","Assessment of Pulmonary Function in Relation to the Anesthetic Used in Patients Undergoing Bariatric Surgery","Inclusion Criteria:\n\n* Obese patients qualified for bariatric surgery.\n\nExclusion Criteria:\n\n* Patients who have absolute contraindications to spirometry testing, i.e:\n\n  * with aneurysms of the aorta or cerebral arteries threatening to rupture, after recent vascular surgery\n  * with increased intracranial pressure, after recent intracranial bleeding or head surgery within the cranial cavity\n  * after acute conditions within 6 months prior to surgery such as stroke, myocardial infarction, unstable angina, pneumothorax\n  * with uncontrolled hypertension\n  * after recent eye surgery or a history of retinal detachment\n  * with hemoptysis of unknown etiology. And patients unable to perform spirometry testing","ALL","18 Years",{"count":120,"type":121},100,"ESTIMATED","INTERVENTIONAL",[124],"NA","It is known that more or less pronounced impairment of pulmonary function occurs after anesthesia. It has been demonstrated in the postoperative period in both patients undergoing general and regional anesthesia, in patients after intra-abdominal and superficial procedures, in overweight and normal-weight patients. It has also been shown that when general anesthesia is performed with the inhalation anesthetic sevoflurane, there is a slightly smaller reduction in lung function parameters than when only intravenous anesthetics are used.\n\nThe purpose of this study is to evaluate lung function before induction and after awakening from general anesthesia depending on the inhalational anesthetic used in obese patients undergoing bariatric surgery",[127],"Obesity and Obesity-related Medical Conditions","2024-12-28",{"date":130,"type":131},"2025-01-06","ACTUAL",{"date":133,"type":121},"2025-01-08",{"date":135,"type":121},"2026-04-01",{"name":5,"class":6},1]