[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100594529":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":34,"responsibleParty":50,"collaborators":10,"id":52,"slug":10,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":10,"eligibilityCriteria":56,"healthyVolunteers":53,"sex":57,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":63,"studyType":64,"phases":10,"briefSummary":65,"conditions":66,"keywords":69,"overallStatus":37,"whyStopped":10,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"University of Nevada, Las Vegas","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Shock Patients",null,"This cohort includes adult patients presenting with clinical signs of shock in the intensive care unit. Each participant will undergo stroke volume measurement using both transthoracic echocardiography and bioreactance-based monitoring (Cheetah NICOM) before and after passive leg raising. No therapeutic intervention will be performed as part of the study.",[13],"Device: Cheetah NICOM",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"DEVICE","Cheetah NICOM","Bioreactance-based noninvasive cardiac output monitoring device used to measure stroke volume before and after passive leg raising. Used solely for observational measurement. No therapeutic intervention is performed.",[9],[21],{"name":22,"affiliation":23,"role":24},"Mutsumi J Kioka, Medical Doctor","UNLV","PRINCIPAL_INVESTIGATOR",[26,30],{"name":22,"role":27,"phone":28,"phoneExt":10,"email":29},"CONTACT","7026712345","mutsumi.kioka@unlv.edu",{"name":31,"role":27,"phone":32,"phoneExt":10,"email":33},"Office of Research Integrity Human Subjects UNLV","7028952794","IRB@unlv.edu",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"University Medical Center Southern Nevada","RECRUITING","Las Vegas","Nevada","89102","United States",{"type":43,"coordinates":44},"Point",[45,46],-115.13722,36.17497,{"lat":46,"lon":45},[49],{"name":22,"role":27,"phone":28,"phoneExt":10,"email":29},{"type":51,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100594529",false,"NCT07020637","Assessment of Stroke Volume in Shock Using Echocardiography Versus Bioreactive Impedance","Inclusion Criteria\n\n* Age ≥ 18 years\n* Clinical diagnosis of shock as determined by the treating ICU physician (e.g., hypotension requiring vasopressors or evidence of end-organ hypoperfusion)\n* Able to obtain informed consent from the patient or a legally authorized representative\n* Enrollment within 24 hours of ICU admission\n\nExclusion Criteria:\n\n* Pregnancy\n* Known severe aortic valve disease or dynamic left ventricular outflow tract obstruction\n* Morbid obesity (BMI \\> 40) that precludes accurate echocardiographic imaging Presence of cardiac arrhythmias (e.g., atrial fibrillation with rapid ventricular response) affecting stroke volume measurements\n* Implanted cardiac assist devices (e.g., LVAD, pacemaker dependency)\n* Imminent death or decision for comfort care only","ALL","18 Years","90 Years",{"count":61,"type":62},30,"ESTIMATED","1 Day","OBSERVATIONAL","This study aims to evaluate the correlation between stroke volume measurements obtained by transthoracic echocardiography and bioreactance-based noninvasive cardiac output monitoring. The primary objective is to assess the level of agreement between these two modalities in critically ill patients.",[67,68],"Shock","Critical Illness",[70,71,72,73,74,75,76],"Cheeta NICOM","Bioreactance","Transthoracic Echocardiography","Passive Leg Raising","Stroke Volume","Shock Assssment","Noninvasive Cardiac Output Monitoring","2026-04-13",{"date":79,"type":80},"2026-04-15","ACTUAL",{"date":82,"type":80},"2024-10-19",{"date":84,"type":62},"2026-04-30",{"name":5,"class":6},1]