Assessment of the Ocular Microbiome in Health and Disease
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorVanderbilt University Medical Center
About this trial
The objective of this application is to illustrate the core constituents of the ocular surface microbiome, describe factors that promote colonization, and assess the ocular microbiome's role in the health of the anterior segment. We will conduct a prospective, observational cohort study, including a longitudinal analysis of the ocular microbiome in adults.
Eligibility criteria
Qualifiers
18 years of age or older
Provide informed consent
Cohort A - normal eyes with no ocular disease
Cohort B - primary open angle glaucoma/Ocular hypertension defined as mild glaucoma which is well controlled with no more than one drop of prostaglandin use daily for the past 6 months
Disqualifiers
Prior ocular disease either of the anterior or posterior segment
Any medical comorbidities except well controlled DH and HTN
Unable to follow up with study procedures as described
Trial design
Treatments tested in this trial
- Eye swab
Treatment groups
500 Participants
are divided into 6 treatment groups6
Treatment groupsSee each treatment group below.
Locations
1Vanderbilt University Medical Center37232, NashvilleTennessee, United States
Sponsors and collaborators
Vanderbilt University Medical Center
Lead sponsor
Source ClinicalTrials.gov