Association Between Exercise, Patient-Reported Outcomes, and Clinical Events in Adult Cancer Survivors

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorMemorial Sloan Kettering Cancer Center

About this trial

This protocol is a retrospective study using observational data to conduct a target trial emulation to examine the association of exercise on cancer specific endpoints and other clinical outcomes in cancer survivors.

Eligibility criteria

Qualifiers

Adult (≥18 years of age) patients with history of primary invasive cancer under surveillance at Memorial Sloan Kettering Cancer Center (MSK).

Completion of an exercise survey (baseline) as part of MSK Cancer Survivorship Program and completion of a historical survey in the MSK Cancer Survivorship Program 9-15 months (time th) prior reporting non-exercising status [i.e., reporting <10 metabolic equivalent-hours per week (MET-h/week)]. Patients completing an additional exercise survey between th and baseline are excluded.

No evidence of recurrent or metastatic disease in the 15 months prior to the baseline exercise assessment

Completion of all definitive primary adjuvant therapy (e.g., chemotherapy, radiotherapy, targeted therapy) at least 3 months prior to completion of the historical exercise survey in a MSK Cancer Survivorship Program. Adjuvant hormonal therapy is permitted at any time.

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Exercise

Treatment groups

1,000 Participants
are divided into 2 treatment groups

Locations

4
City of Hope Cancer Center (Data Analysis Only)91010, DuarteCalifornia, United States
University of California, Los Angeles (Data or Specimen Analysis Only)90095-1781, Los AngelesCalifornia, United States
Memorial Sloan Kettering Cancer Center (All Protocol Activities)10065, New YorkNew York, United States
Weill Cornell Medical College (Data or Specimen Analysis Only)10021, New YorkNew York, United States

Sponsors and collaborators

Memorial Sloan Kettering Cancer Center

Lead sponsor