[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100575149":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":13,"centralContacts":21,"locations":26,"responsibleParty":43,"collaborators":7,"id":45,"slug":7,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":46,"sex":52,"minAge":53,"maxAge":7,"enrollmentInfo":54,"targetDuration":7,"studyType":57,"phases":7,"briefSummary":58,"conditions":59,"keywords":63,"overallStatus":29,"whyStopped":7,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},{"fullName":5,"class":6},"University of Sao Paulo General Hospital","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"DIAGNOSTIC_TEST","Galectin-3 dosage","Peripheral blood sample will be collected in the 24h before CABG",[14,18],{"name":15,"affiliation":16,"role":17},"Leticia Carvalho","Instituto do Coração - HCFMUSP","PRINCIPAL_INVESTIGATOR",{"name":19,"affiliation":16,"role":20},"Eduardo Lima","STUDY_DIRECTOR",[22],{"name":19,"role":23,"phone":24,"phoneExt":7,"email":25},"CONTACT","+ 5511 26615352","eduglima@yahoo.com.br",[27],{"facility":28,"status":29,"city":30,"state":30,"zip":31,"country":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"Instituto do Coração - Hospital das Clínicas - Faculdade de Medicina da Universidade de São Paulo","RECRUITING","São Paulo","05403000","Brazil",{"type":34,"coordinates":35},"Point",[36,37],-46.63611,-23.5475,{"lat":37,"lon":36},[40],{"name":41,"role":23,"phone":42,"phoneExt":7,"email":25},"Eduardo Gomes Lima, PhD","551126615352",{"type":44,"investigatorFullName":7,"investigatorTitle":7,"investigatorAffiliation":7,"oldNameTitle":7,"oldOrganization":7},"SPONSOR","100575149",false,"NCT06768528","Association Between GalectiN-3 and POSt-operative AtrIal Fibrillation After Coronary Artery BypaSs Graft","Association Between Galectin-3 and Post-operative AtrIal Fibrillation After Coronary Artery Bypass Graft","GNOSIS","Inclusion Criteria:\n\n* Patients undergoing coronary artery bypass graft surgery\n\nExclusion Criteria:\n\n* Inability to sign the free and informed consent form\n* Renal dysfunction with estimated glomerular filtration rate less than 30ml \u002F min \u002F 1.73m² or dialysis therapy\n* Moderate to severe left ventricular dysfunction (ejection fraction \\\u003C 40%)\n* Patients with previous atrial fibrillation\n* Pregnancy\n* Concomitant valve surgery","ALL","18 Years",{"count":55,"type":56},90,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to test the association between high levels of Galectin-3 and the occurrence of post-operative atrial fibrillation after isolated coronary artery bypass grafting (CABG). The main question\\[s\\] it aims to answer are:\n\n* Is Galectin-3 an accurate biomarker to predict higher risk of developing post-operative atrial fibrillation?\n* Are high levels of Galectin-3 associated to other post-operative complications and major adverse cardiovascular events? Participants will be enrolled during pre-operative evaluation and a peripheral blood sample collection will be performed in the 24h before CABG. Participants will then be followed for a period of 12 months (daily during hospitalization and 3 appointments after hospital discharge) to determine whether patients with higher levels of Galectin-3 will have worse outcomes.",[60,61,62],"Post-operative Atrial Fibrillation","Cardiovascular Diseases","Post-pericardiotomy Syndrome",[64,65],"Post-operative atrial fibrillation","Galectin-3","2025-01-06",{"date":68,"type":69},"2025-01-10","ACTUAL",{"date":71,"type":69},"2023-01-01",{"date":73,"type":56},"2026-12-01",{"name":5,"class":6},1]