[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100602161":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":10,"centralContacts":24,"locations":30,"responsibleParty":48,"collaborators":10,"id":52,"slug":10,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":55,"acronym":10,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":58,"minAge":59,"maxAge":10,"enrollmentInfo":60,"targetDuration":10,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":67,"overallStatus":73,"whyStopped":10,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Sohag University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Control Group",null,"Normal healthy volunteers aged \\> 30 years",[13],"Genetic: genotyping assay by polymerase chain reaction",{"label":15,"type":10,"description":16,"interventionNames":17},"Experimental Group","Patients aged \\>30 years and diagnosed with Primary Open Angle Glaucoma",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":10},"GENETIC","genotyping assay by polymerase chain reaction","Blood sample will be obtained from all participants by withdrawing 3 mL of blood via venipuncture in ethylenediaminetetraacetic acid tube.\n\nThereafter, DNA extraction will be obtained after centrifugation to be used for genotyping assay of MMP-9 gene with polymerase chain reaction",[9,15],[25],{"name":26,"role":27,"phone":28,"phoneExt":10,"email":29},"Thomas Talaat Nageh, Demonstrator","CONTACT","20 1276890796","thomas.talaat@med.sohag.edu.eg",[31],{"facility":32,"status":10,"city":33,"state":34,"zip":35,"country":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"Sohag University Hosipital","Sohag","Sohag Governorate","82525","Egypt",{"type":38,"coordinates":39},"Point",[40,41],31.69478,26.55695,{"lat":41,"lon":40},[44],{"name":45,"role":27,"phone":46,"phoneExt":10,"email":47},"Magdy Mohamed Amin El Kady, Professor","( 093 ) 4602963","portal@med.sohag.edu.eg",{"type":49,"investigatorFullName":50,"investigatorTitle":51,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Thomas Talaat Nageh","Demonstrator","100602161",false,"NCT07119905","Association Between Matrix Metalloproteinase-9 Gene Polymorphism and Susceptibility to Primary Open Angle Glaucoma Patients in Sohag University Hospital","Inclusion Criteria:\n\n* Men and women older than 30 years\n* Primary open angle glaucoma as evidenced from characteristic visual field loss and optic disc cupping (POAG group)\n* Healthy subjects matched by age, sex and ethnicity to the POAG patients group (control group)\n\nExclusion Criteria:\n\n* Exfoliation glaucoma, pigmentary glaucoma\n* History of acute angle closure",true,"ALL","30 Years",{"count":61,"type":62},80,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to investigate the potential association between MMP-9 gene polymorphism and susceptibility to Primary Open Angle Glaucoma development in Egyptian patients The main question it aims to",[66],"Primary Open Angle Glaucoma (POAG)",[68,69,70,71,72],"Primary Open Angle Glaucoma","POAG","Gene Polymorphism","MMP-9","Matrix Metalloproteinase-9 Gene Polymorphism","NOT_YET_RECRUITING","2025-08-06",{"date":76,"type":77},"2025-08-13","ACTUAL",{"date":79,"type":62},"2026-06-01",{"date":81,"type":62},"2027-02-01",{"name":5,"class":6},1]