This study aims to estimate the prevalence of Metabolic dysfunction - associated Steatoic liver disease (MASLD) among adults with primary hypothyroidism (overt or sub-clinical 1ry hypothyroidism) and prevalence of MASLD in Hashimoto-thyroiditis vs Euthyroid controls in non-diabetic patients.
Diagnosed with primary hypothyroidism (overt or sub clinical hypothyroidism) within 3 months with or without levothyroxine treatment.
Patients with positive antibody (positive TPO antibody or positive Thyroglobin antibody) irrespective of thyroid status
Metabolic dysfunction-associated steatotic liver disease (MASLD) assessment by ultrasound and Fibro-scan.
Diabetic patients according to American Diabetes Association (ADA) Criteria.
Excessive Alcohol consumption (> 30 gm/ day in men, 20 gm /day in women.
Body mass index (BMI) index >40 kg/m2
Other causes of chronic hepatic steatosis [e.g., positive hepatitis B virus (HBV), positive hepatitis C virus (HCV)), autoimmune disease, Wilson disease, drugs].
Sohag University
Lead sponsor